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View Structure Prediction Details

Protein: RAD51
Organism: Saccharomyces cerevisiae
Length: 400 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD51.

Description E-value Query
Range		 Subject
Range
RAD51_YEAST - DNA repair protein RAD51 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD51 PE=1 SV=1
gi|207345902 - gi|207345902|gb|EDZ72571.1| YER095Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190405660 - gi|190405660|gb|EDV08927.1| DNA repair protein RAD51 [Saccharomyces cerevisiae RM11-1a]
RAD51 - Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in t...
 0.0 [1..400] [1..400]
RAD51_CHICK - DNA repair protein RAD51 homolog 1 OS=Gallus gallus GN=RAD51A PE=2 SV=1
 0.0 [57..397] [1..339]
RAD51_CRIGR - DNA repair protein RAD51 homolog 1 OS=Cricetulus griseus GN=RAD51 PE=2 SV=1
 0.0 [57..397] [1..339]
RAD51_MOUSE - DNA repair protein RAD51 homolog 1 OS=Mus musculus GN=Rad51 PE=1 SV=1
 0.0 [57..397] [1..339]
gi|4996226 - gi|4996226|dbj|BAA78377.1| Rad51 [Cynops pyrrhogaster]
 0.0 [63..397] [3..337]
RA51A_XENLA - DNA repair protein RAD51 homolog A OS=Xenopus laevis GN=rad51-a PE=2 SV=1
 0.0 [69..397] [8..336]
RA51_USTMA, RAD5... - DNA repair protein RAD51 OS=Ustilago maydis GN=RAD51 PE=3 SV=1, (Q99133) DNA repair protein RAD51
RAD51_USTMA - DNA repair protein RAD51 OS=Ustilago maydis (strain 521 / FGSC 9021) GN=RAD51 PE=3 SV=1
 0.0 [63..397] [1..339]
RAD51_RABIT - DNA repair protein RAD51 homolog 1 OS=Oryctolagus cuniculus GN=RAD51 PE=2 SV=1
 0.0 [57..397] [1..339]
gi|395377 - gi|395377|emb|CAA80878.1| RecA-like protein [Schizosaccharomyces pombe]
 0.0 [47..397] [6..353]

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Predicted Domain #1
Region A:
Residues: [1-126] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQVQEQHIS ESQLQYGNGS LMSTVPADLS QSVVDGNGNG SSEDIEATNG SGDGGGLQEQ  60
   61 AEAQGEMEDE AYDEAALGSF VPIEKLQVNG ITMADVKKLR ESGLHTAEAV AYAPRKDLLE 120
  121 IKGISE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 311.69897
Match: 1b22A_
Description: DNA repair protein Rad51, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-dependent ATPase activity 6.08870471440355 bayes_pls_golite062009
DNA helicase activity 5.90932638467326 bayes_pls_golite062009
ATP-dependent DNA helicase activity 5.45262775532714 bayes_pls_golite062009
helicase activity 4.28397455986496 bayes_pls_golite062009
purine NTP-dependent helicase activity 3.663510450664 bayes_pls_golite062009
ATP-dependent helicase activity 3.663510450664 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.65328018648613 bayes_pls_golite062009
ATPase activity, coupled 2.62906136657082 bayes_pls_golite062009
pyrophosphatase activity 2.58149479936199 bayes_pls_golite062009
hydrolase activity 2.5712103536265 bayes_pls_golite062009
ATPase activity 2.56628820450144 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.56034830999299 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.56013654932837 bayes_pls_golite062009
binding 1.9180887037845 bayes_pls_golite062009
nucleic acid binding 1.9087142423581 bayes_pls_golite062009
DNA binding 1.87185414119548 bayes_pls_golite062009
catalytic activity 1.58067730905989 bayes_pls_golite062009
protein binding 1.45202848418786 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [127-400] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKADKLLNEA ARLVPMGFVT AADFHMRRSE LICLTTGSKN LDTLLGGGVE TGSITELFGE  60
   61 FRTGKSQLCH TLAVTCQIPL DIGGGEGKCL YIDTEGTFRP VRLVSIAQRF GLDPDDALNN 120
  121 VAYARAYNAD HQLRLLDAAA QMMSESRFSL IVVDSVMALY RTDFSGRGEL SARQMHLAKF 180
  181 MRALQRLADQ FGVAVVVTNQ VVAQVDGGMA FNPDPKKPIG GNIMAHSSTT RLGFKKGKGC 240
  241 QRLCKVVDSP CLPEAECVFA IYEDGVGDPR EEDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 151.154902
Match: 1rea__
Description: RecA protein, ATPase-domain; RecA protein, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA clamp loader activity 3.22518920754305 bayes_pls_golite062009
protein-DNA loading ATPase activity 3.19273435123154 bayes_pls_golite062009
transporter activity 3.13325129560423 bayes_pls_golite062009
transmembrane transporter activity 2.92327745911863 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.66107861968804 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
bubble DNA binding 2.62179925837003 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.36915495988847 bayes_pls_golite062009
pyrophosphatase activity 2.29436982996465 bayes_pls_golite062009
DNA-directed DNA polymerase activity 2.29320453203372 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.27303683020046 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.27190707957159 bayes_pls_golite062009
DNA polymerase activity 2.24959734952703 bayes_pls_golite062009
nucleic acid binding 2.21184938313192 bayes_pls_golite062009
hydrolase activity 2.18454736627863 bayes_pls_golite062009
double-strand/single-strand DNA junction binding 2.02697209084624 bayes_pls_golite062009
telomeric DNA binding 1.98044285764127 bayes_pls_golite062009
DNA binding 1.94055378599526 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
transcription regulator activity 1.83584389083042 bayes_pls_golite062009
ATPase activity 1.76238574289941 bayes_pls_golite062009
substrate-specific transporter activity 1.72529279238106 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
microtubule motor activity 1.6537049553461 bayes_pls_golite062009
ATPase activity, coupled 1.57826779898847 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.37694050923424 bayes_pls_golite062009
motor activity 1.34881124154297 bayes_pls_golite062009
structure-specific DNA binding 1.2539059700735 bayes_pls_golite062009
protein transporter activity 1.25342367751911 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
double-stranded DNA binding 1.117585097627 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
single-stranded telomeric DNA binding 0.847538346941812 bayes_pls_golite062009
double-stranded telomeric DNA binding 0.75018916645383 bayes_pls_golite062009
transcription activator activity 0.739301862805678 bayes_pls_golite062009
purine nucleotide binding 0.725611289205392 bayes_pls_golite062009
nucleotide binding 0.717697610309727 bayes_pls_golite062009
purine ribonucleotide binding 0.713814218071151 bayes_pls_golite062009
ribonucleotide binding 0.713752628021599 bayes_pls_golite062009
transcription factor activity 0.697256579145077 bayes_pls_golite062009
single-stranded DNA binding 0.568457189190858 bayes_pls_golite062009
ion transmembrane transporter activity 0.560681051761979 bayes_pls_golite062009
cytoskeletal protein binding 0.500462538667228 bayes_pls_golite062009
recombinase activity 0.45851158693664 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
nucleotidyltransferase activity 0.367559137329714 bayes_pls_golite062009
RNA helicase activity 0.34746349346164 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
histone acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
centromeric DNA binding 0.322818640526369 bayes_pls_golite062009
mismatched DNA binding 0.31144582840038 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.30832907234141 bayes_pls_golite062009
guanyl nucleotide binding 0.296406132096546 bayes_pls_golite062009
GTP binding 0.295705904888768 bayes_pls_golite062009
RNA-dependent ATPase activity 0.29532978396745 bayes_pls_golite062009
guanyl ribonucleotide binding 0.29028316917561 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.248710418805919 bayes_pls_golite062009
structural constituent of ribosome 0.208665086324262 bayes_pls_golite062009
ATP binding 0.19169045543599 bayes_pls_golite062009
adenyl ribonucleotide binding 0.165732470448462 bayes_pls_golite062009
adenyl nucleotide binding 0.162060759063149 bayes_pls_golite062009
active transmembrane transporter activity 0.114463153989353 bayes_pls_golite062009
microfilament motor activity 0.10236059675512 bayes_pls_golite062009
3'-5' DNA helicase activity 0.0769112340058804 bayes_pls_golite062009
cation transmembrane transporter activity 0.0704128024645565 bayes_pls_golite062009
protein transmembrane transporter activity 0.0378638259240902 bayes_pls_golite062009
actin binding 0.00482938540552702 bayes_pls_golite062009
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