| Protein: | RGD2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 714 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RGD2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..714] | [1..714] |
|
|
0.0 | [13..710] | [52..709] |
|
|
0.0 | [1..712] | [2..658] |
|
|
0.0 | [13..707] | [28..709] |
|
|
3.0E-97 | [16..704] | [44..692] |
|
Region A: Residues: [1-225] |
1 11 21 31 41 51
| | | | | |
1 MLSFCDYFWS EDLVSGLDVL FDRLYHGCEQ CDLFIQLFAS RMQFEVSHGR QLFGIEAGMD 60
61 NLKAVQEDED EGVTVSRALR GILQEMSQEG THHLTIASNI ESLVLQPFSK WCIEHRERIQ 120
121 YSEKTLLTNV NNFRKSKKYV GKLEKEYFNK CRQLEEFKRT HFNEDELANA MKSLKIQNKY 180
181 EEDVAREKDH RFFNRIAGID FDYKTMKETL QLLLTKLPKT DYKLP
|
| Detection Method: |  |
| Confidence: | 9.07 |
| Match: | 1av1A |
| Description: | Apolipoprotein A-I |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytoskeletal protein binding | 3.124619761789 | bayes_pls_golite062009 |
| binding | 2.22529267810903 | bayes_pls_golite062009 |
| protein binding | 1.87308005875135 | bayes_pls_golite062009 |
| identical protein binding | 0.909409198394921 | bayes_pls_golite062009 |
| enzyme binding | 0.58709209959999 | bayes_pls_golite062009 |
| GTPase binding | 0.50066793947946 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.459881864914566 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.456472132383968 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.180886944097381 | bayes_pls_golite062009 |
| small GTPase binding | 0.0531578648468707 | bayes_pls_golite062009 |
|
Region A: Residues: [226-299] |
1 11 21 31 41 51
| | | | | |
1 LISYSLSNTN NGGEITKFLL DHMSLKDIDQ AETFGQDLLN LGFLKYCNGV GNTFVNSKKF 60
61 QYQWKNTAYM FANV
|
| Detection Method: | |
| Confidence: | 12.180456 |
| Match: | PF00610 |
| Description: | Domain found in Dishevelled, Egl-10, and Pleckstrin |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [300-366] |
1 11 21 31 41 51
| | | | | |
1 PMPGSEEPTT GESLISRFNN WDGSSAKEII QSKIGNDQGA AKIQAPHISD NERTLFRMMD 60
61 ALAASDK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| GTPase regulator activity | 5.23789256375467 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 5.21562004568462 | bayes_pls_golite062009 |
| small GTPase regulator activity | 4.91645234075732 | bayes_pls_golite062009 |
| GTPase activator activity | 4.81440293338491 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 4.76400460221691 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 4.58620967349979 | bayes_pls_golite062009 |
| enzyme regulator activity | 4.5322075775333 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 4.48279904625182 | bayes_pls_golite062009 |
| enzyme activator activity | 4.29367232260052 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.68681762274025 | bayes_pls_golite062009 |
| actin binding | 3.68337819140185 | bayes_pls_golite062009 |
| actin filament binding | 2.37781909937968 | bayes_pls_golite062009 |
| microfilament motor activity | 2.15518436158221 | bayes_pls_golite062009 |
| binding | 1.62780792681766 | bayes_pls_golite062009 |
| protein binding | 1.21496582666968 | bayes_pls_golite062009 |
| Rho guanyl-nucleotide exchange factor activity | 0.967362611034944 | bayes_pls_golite062009 |
| enzyme binding | 0.56024350956935 | bayes_pls_golite062009 |
| GTPase binding | 0.54882559587114 | bayes_pls_golite062009 |
| small GTPase binding | 0.36738560339155 | bayes_pls_golite062009 |
|
Region A: Residues: [367-569] |
1 11 21 31 41 51
| | | | | |
1 KYYQECFKMD ALRCSVEELL IDHLSFMEKC ESDRLNAIKK ATLDFCSTLG NKISSLRLCI 60
61 DKMLTLENDI DPTADLLQLL VKYKTGSFKP QAIVYNNYYN PGSFQNFGVD LETRCRLDKK 120
121 VVPLIISSIF SYMDKIYPDL PNDKVRTSIW TDSVKLSLTH QLRNLLNKQQ FHNEGEIFDI 180
181 LSTSKLEPST IASVVKIYLL ELP
|
| Detection Method: | |
| Confidence: | 38.0 |
| Match: | 1rgp__ |
| Description: | p50 RhoGAP domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [570-714] |
1 11 21 31 41 51
| | | | | |
1 DPLIPNDVSD ILRVLYLDYP PLVETALQNS TSSPENQQDD DNEEGFDTKR IRGLYTTLSS 60
61 LSKPHIATLD AITTHFYRLI KILKMGENGN EVADEFTVSI SQEFANCIIQ SKITDDNEIG 120
121 FKIFYDLLTH KKQIFHELKR QNSKN
|
| Detection Method: | |
| Confidence: | 38.0 |
| Match: | 1rgp__ |
| Description: | p50 RhoGAP domain |
| Matching Structure (courtesy of the PDB): |
|
