YRC Public Data Repository - Protein Structure Prediction

Protein:	SEC9
Organism:	Saccharomyces cerevisiae
Length:	651 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC9.

Description	E-value	Query Range	Subject Range
SEC9_YEAST - Protein transport protein SEC9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC9 PE=1... SEC9 - t-SNARE protein important for fusion of secretory vesicles with the plasma membrane; similar to but ...	0.0	[1..651]	[1..651]
gi\|14250231, gi\|... - ref\|NP_659210.1\| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi\|14250231\|gb...	3.0E-55	[189..648]	[936..1383]
gi\|3668187 - gi\|3668187\|dbj\|BAA33452.1\| myosin heavy chain [Theragra chalcogramma]	2.0E-52	[189..550]	[931..1287]
gi\|2351219 - gi\|2351219\|dbj\|BAA22067.1\| myosin heavy chain [Cyprinus carpio]	6.0E-49	[126..648]	[845..1375]
gi\|12657350 - gi\|12657350\|emb\|CAC27776.1\| myosin heavy chain [Notothenia coriiceps]	2.0E-48	[189..648]	[923..1370]
gi\|15384839 - gi\|15384839\|emb\|CAC59753.1\| myosin heavy chain [Paracirrhites forsteri]	2.0E-48	[178..648]	[920..1378]
gi\|29727 - gi\|29727\|emb\|CAA37068.1\| cardiac beta myosin heavy chain [Homo sapiens]	4.0E-48	[221..648]	[960..1376]
MYSS_CHICK - Myosin heavy chain, skeletal muscle, adult OS=Gallus gallus PE=1 SV=4	7.0E-48	[189..648]	[932..1379]

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Predicted Domain #1

Region A:
Residues: [1-204]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLKKFFKIK PPEEATPEQN KDTLMELGIS VKNPSKKRKE KFAAYGKFAN DKAEDKVYAP  60
   61 PGYEQYARPQ DELEDLNASP LDANANEATA GSNRGSSGTQ DLGNGAESNS MQDPYAIEND 120
  121 DYRYDDDPYA RFQANKSNGR GSVNAAPYGD YGGGYNGTSL NSYNNDGPYS NQNTSNSWVN 180
  181 ANGRNSLNHS NSTLNVGPSR QTRQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [205-302]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPVSTSTNSL SLDQRSPLAN PMQEKRNPYA DMNSYGGAYD SNTNRSSGTR QGSSKNANPY  60
   61 ASMANDSYSN GNLNRSANPY SSRSVRQPQS QQAPMTYT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.0
Match:	1bg1A_
Description:	STAT3b
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [303-651]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSFIASDEAA RNSEVDLNEE PRTGEFDFEE VYADKSAENR AALDEPDLNA VMTNEDSIDL  60
   61 NASEVDHSSR QQQQQQWFMD EQQQQQQHFN ATNNQYGDQR GYKTFEEIQK EEEARQQQEE 120
  121 DEAVDEIKQE IKFTKQSSVA STRNTLKMAQ DAERAGMNTL GMLGHQSEQL NNVEGNLDLM 180
  181 KVQNKVADEK VAELKKLNRS ILAVHVSNPF NSKRRRRERE EQLKNRKIEE KLMREQTSQQ 240
  241 LSQSTQRIEG AMNANNNISE VRERYQRKNV LEKAKRYQFE NDEEDDEMEL EIDRNLDQIQ 300
  301 QVSNRLKKMA LTTGKELDSQ QKRLNNIEES TDDLDINLHM NTNRLAGIR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.69897
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits