Protein: | RRP4 |
Organism: | Saccharomyces cerevisiae |
Length: | 359 amino acids |
Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRP4.
Description | E-value | Query Range |
Subject Range |
|
9.0E-76 | [4..349] | [1..328] |
|
1.0E-71 | [35..347] | [7..283] |
|
2.0E-68 | [38..347] | [10..283] |
|
1.0E-61 | [45..345] | [20..286] |
|
9.0E-51 | [39..339] | [16..282] |
|
1.0E-48 | [34..326] | [19..289] |
|
9.0E-48 | [45..294] | [2..250] |
|
1.0E-47 | [45..295] | [2..251] |
|
4.0E-46 | [45..280] | [2..238] |
|
1.0E-42 | [34..314] | [150..409] |
Region A: Residues: [1-189] |
1 11 21 31 41 51 | | | | | | 1 MSEVITITKR NGAFQNSSNL SYNNTGISDD ENDEEDIYMH DVNSASKSES DSQIVTPGEL 60 61 VTDDPIWMRG HGTYFLDNMT YSSVAGTVSR VNRLLSVIPL KGRYAPETGD HVVGRIAEVG 120 121 NKRWKVDIGG KQHAVLMLGS VNLPGGILRR KSESDELQMR SFLKEGDLLN AEVQSLFQDG 180 181 SASLHTRSL |
Detection Method: | |
Confidence: | 23.69897 |
Match: | 1e3pA_ |
Description: | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
RNA binding | 5.18414740305744 | bayes_pls_golite062009 |
exoribonuclease activity | 4.57899887224013 | bayes_pls_golite062009 |
exoribonuclease activity, producing 5'-phosphomonoesters | 4.54136587416505 | bayes_pls_golite062009 |
ribonuclease activity | 4.53127626527286 | bayes_pls_golite062009 |
structural constituent of ribosome | 3.89236528662255 | bayes_pls_golite062009 |
mRNA binding | 3.82977088614136 | bayes_pls_golite062009 |
nucleic acid binding | 3.68444148122352 | bayes_pls_golite062009 |
structural molecule activity | 3.54418030121155 | bayes_pls_golite062009 |
3'-5'-exoribonuclease activity | 3.40736445988244 | bayes_pls_golite062009 |
binding | 2.8667878224392 | bayes_pls_golite062009 |
1.63970610538963 | bayes_pls_golite062009 | |
hydrolase activity, acting on ester bonds | 1.62417180482862 | bayes_pls_golite062009 |
3'-5' exonuclease activity | 1.55351486913613 | bayes_pls_golite062009 |
transcription regulator activity | 1.43703138180882 | bayes_pls_golite062009 |
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.42151567812515 | bayes_pls_golite062009 |
aminoacyl-tRNA ligase activity | 1.35850109411274 | bayes_pls_golite062009 |
ligase activity, forming aminoacyl-tRNA and related compounds | 1.35845277283398 | bayes_pls_golite062009 |
ligase activity, forming carbon-oxygen bonds | 1.35845277283398 | bayes_pls_golite062009 |
exonuclease activity | 1.25488463068335 | bayes_pls_golite062009 |
DNA binding | 1.20852534725468 | bayes_pls_golite062009 |
exoribonuclease II activity | 1.18248519339188 | bayes_pls_golite062009 |
protein binding | 0.934192915895039 | bayes_pls_golite062009 |
hydrolase activity | 0.704891843968224 | bayes_pls_golite062009 |
mRNA 3'-UTR binding | 0.489176583045793 | bayes_pls_golite062009 |
transcription factor activity | 0.386248501195543 | bayes_pls_golite062009 |
ligase activity | 0.346041081217685 | bayes_pls_golite062009 |
structure-specific DNA binding | 0.32222928997178 | bayes_pls_golite062009 |
poly-pyrimidine tract binding | 0.30467150200016 | bayes_pls_golite062009 |
catalytic activity | 0.161830442565647 | bayes_pls_golite062009 |
aspartate-tRNA ligase activity | 0.151650064901878 | bayes_pls_golite062009 |
translation initiation factor activity | 0.11625379846973 | bayes_pls_golite062009 |
single-stranded DNA binding | 0.1069917291606 | bayes_pls_golite062009 |
DNA-directed RNA polymerase activity | 0.0740938021136293 | bayes_pls_golite062009 |
RNA polymerase activity | 0.0740938021136293 | bayes_pls_golite062009 |
Region A: Residues: [190-287] |
1 11 21 31 41 51 | | | | | | 1 KYGKLRNGMF CQVPSSLIVR AKNHTHNLPG NITVVLGVNG YIWLRKTSQM DLARDTPSAN 60 61 NSSSIKSTGP TGAVSLNPSI TRLEEESSWQ IYSDENDP |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [288-359] |
1 11 21 31 41 51 | | | | | | 1 SISNNIRQAI CRYANVIKAL AFCEIGITQQ RIVSAYEASM VYSNVGELIE KNVMESIGSD 60 61 ILTAEKMRGN GN |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
View | Download | 0.830 | 0.688 | 3'-5'-exoribonuclease activity | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |