| Protein: | SLN1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1220 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLN1.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [1..1220] | [1..1220] |
|
|
0.0 | [333..1208] | [272..1204] |
|
|
0.0 | [299..1210] | [158..1042] |
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0.0 | [328..1208] | [286..1221] |
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0.0 | [328..1208] | [287..1226] |
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0.0 | [480..1211] | [402..1110] |
|
Region A: Residues: [1-161] |
1 11 21 31 41 51
| | | | | |
1 MRFGLPSKLE LTPPFRIGIR TQLTALVSIV ALGSLIILAV TTGVYFTSNY KNLRSDRLYI 60
61 AAQLKSSQID QTLNYLYYQA YYLASRDALQ SSLTSYVAGN KSADNWVDSL SVIQKFLSSS 120
121 NLFYVAKVYD SSFNAVLNAT NNGTGDLIPE DVLDSLFPLS T
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [162-264] |
1 11 21 31 41 51
| | | | | |
1 DTPLPSSLET IGILTDPVLN STDYLMSMSL PIFANPSIIL TDSRVYGYIT IIMSAEGLKS 60
61 VFNDTTALEH STIAIISAVY NSQGKASGYH FVFPPYGSRS DLP
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.408 | b.1.2 | Fibronectin type III |
| View | Download | 0.420 | b.61.3 | D-aminopeptidase, middle and C-terminal domains |
| View | Download | 0.366 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.285 | b.61.4 | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
| View | Download | 0.277 | b.1.1 | Immunoglobulin |
| View | Download | 0.277 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.272 | c.52.2 | tRNA splicing endonuclease, C-terminal domain |
| View | Download | 0.243 | b.1.2 | Fibronectin type III |
| View | Download | 0.239 | d.17.1 | Cystatin/monellin |
| View | Download | 0.228 | b.1.1 | Immunoglobulin |
| View | Download | 0.219 | b.3.4 | Transthyretin (prealbumin) |
| View | Download | 0.212 | b.1.2 | Fibronectin type III |
| View | Download | 0.211 | d.58.10 | Acylphosphatase-like |
|
Region A: Residues: [265-553] |
1 11 21 31 41 51
| | | | | |
1 QKVFSIKNDT FISSAFRNGK GGSLKQTNIL STRNTALGYS PCSFNLVNWV AIVSQPESVF 60
61 LSPATKLAKI ITGTVIAIGV FVILLTLPLA HWAVQPIVRL QKATELITEG RGLRPSTPRT 120
121 ISRASSFKRG FSSGFAVPSS LLQFNTAEAG STTSVSGHGG SGHGSGAAFS ANSSMKSAIN 180
181 LGNEKMSPPE EENKIPNNHT DAKISMDGSL NHDLLGPHSL RHNDTDRSSN RSHILTTSAN 240
241 LTEARLPDYR RLFSDELSDL TETFNTMTDA LDQHYALLEE RVRARTKQL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [554-670] |
1 11 21 31 41 51
| | | | | |
1 EAAKIEAEAA NEAKTVFIAN ISHELRTPLN GILGMTAISM EETDVNKIRN SLKLIFRSGE 60
61 LLLHILTELL TFSKNVLQRT KLEKRDFCIT DVALQIKSIF GKVAKDQRVR LSISLFP
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| Detection Method: | |
| Confidence: | 14.04 |
| Match: | 1joyA |
| Description: | EnvZ histidine kinase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [671-785] |
1 11 21 31 41 51
| | | | | |
1 NLIRTMVLWG DSNRIIQIVM NLVSNALKFT PVDGTVDVRM KLLGEYDKEL SEKKQYKEVY 60
61 IKKGTEVTEN LETTDKYDLP TLSNHRKSVD LESSATSLGS NRDTSTIQEE ITKRN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.702 | 0.111 | osmosensory signaling pathway via two-component system | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.795 | 0.098 | osmosensory signaling pathway via two-component system | d.80.1 | Tautomerase/MIF |
| View | Download | 0.806 | 0.009 | osmosensory signaling pathway via two-component system | c.44.2 | Enzyme IIB-cellobiose |
| View | Download | 0.758 | 0.009 | osmosensory signaling pathway via two-component system | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.726 | 0.008 | osmosensory signaling pathway via two-component system | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.595 | N/A | N/A | d.58.13 | Anticodon-binding domain of PheRS |
| View | Download | 0.585 | N/A | N/A | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.583 | N/A | N/A | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.531 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.520 | N/A | N/A | d.199.1 | DNA-binding C-terminal domain of the transcription factor MotA |
| View | Download | 0.508 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.506 | N/A | N/A | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.479 | N/A | N/A | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.477 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.471 | N/A | N/A | c.16.1 | Lumazine synthase |
| View | Download | 0.467 | N/A | N/A | c.30.1 | PreATP-grasp domain |
| View | Download | 0.447 | N/A | N/A | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.443 | N/A | N/A | c.23.12 | Formate/glycerate dehydrogenase catalytic domain-like |
| View | Download | 0.436 | N/A | N/A | d.67.2 | Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain |
| View | Download | 0.430 | N/A | N/A | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.428 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.417 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.415 | N/A | N/A | d.58.5 | GlnB-like |
| View | Download | 0.412 | N/A | N/A | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.409 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.402 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.394 | N/A | N/A | d.58.43 | Mechanosensitive channel protein MscS (YggB), C-terminal domain |
| View | Download | 0.383 | N/A | N/A | d.52.2 | GMP synthetase C-terminal dimerisation domain |
| View | Download | 0.382 | N/A | N/A | d.32.1 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| View | Download | 0.382 | N/A | N/A | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.372 | N/A | N/A | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.359 | N/A | N/A | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.359 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.356 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.353 | N/A | N/A | c.24.1 | Methylglyoxal synthase-like |
| View | Download | 0.348 | N/A | N/A | d.58.14 | Ribosomal protein S6 |
| View | Download | 0.348 | N/A | N/A | c.23.5 | Flavoproteins |
| View | Download | 0.340 | N/A | N/A | d.227.1 | OsmC-like |
| View | Download | 0.335 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.333 | N/A | N/A | c.30.1 | PreATP-grasp domain |
| View | Download | 0.332 | N/A | N/A | c.57.1 | Molybdenum cofactor biosynthesis proteins |
| View | Download | 0.328 | N/A | N/A | c.52.2 | tRNA splicing endonuclease, C-terminal domain |
| View | Download | 0.316 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.310 | N/A | N/A | d.52.7 | Ribosome-binding factor A, RbfA |
| View | Download | 0.296 | N/A | N/A | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.292 | N/A | N/A | d.65.1 | Hedgehog/DD-pepidase |
| View | Download | 0.281 | N/A | N/A | d.58.12 | eEF-1beta-like |
| View | Download | 0.278 | N/A | N/A | d.58.49 | YajQ-like |
| View | Download | 0.276 | N/A | N/A | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.274 | N/A | N/A | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.274 | N/A | N/A | a.165.1 | Myosin phosphatase inhibitor 17kDa protein, CPI-17 |
| View | Download | 0.269 | N/A | N/A | c.44.1 | Phosphotyrosine protein phosphatases I |
| View | Download | 0.259 | N/A | N/A | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.247 | N/A | N/A | c.44.1 | Phosphotyrosine protein phosphatases I |
| View | Download | 0.246 | N/A | N/A | c.23.12 | Formate/glycerate dehydrogenase catalytic domain-like |
| View | Download | 0.244 | N/A | N/A | d.45.1 | ClpS-like |
| View | Download | 0.241 | N/A | N/A | d.130.1 | S-adenosylmethionine synthetase |
| View | Download | 0.236 | N/A | N/A | d.92.2 | beta-N-acetylhexosaminidase-like domain |
| View | Download | 0.218 | N/A | N/A | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.217 | N/A | N/A | d.237.1 | Hypothetical protein YjiA, C-terminal domain |
| View | Download | 0.209 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.205 | N/A | N/A | c.23.16 | Class I glutamine amidotransferase-like |
| View | Download | 0.203 | N/A | N/A | d.68.1 | Translation initiation factor IF3, C-terminal domain |
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Region A: Residues: [786-939] |
1 11 21 31 41 51
| | | | | |
1 TVANESIYKK VNDREKASND DVSSIVSTTT SSYDNAIFNS QFNKAPGSDD EEGGNLGRPI 60
61 ENPKTWVISI EVEDTGPGID PSLQESVFHP FVQGDQTLSR QYGGTGLGLS ICRQLANMMH 120
121 GTMKLESKVG VGSKFTFTLP LNQTKEISFA DMEF
|
| Detection Method: | |
| Confidence: | 81.68867 |
| Match: | 1bxdA_ |
| Description: | Histidine kinase domain of the osmosensor EnvZ |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| two-component response regulator activity | 6.41182973389827 | bayes_pls_golite062009 |
| molecular transducer activity | 6.27803885496668 | bayes_pls_golite062009 |
| signal transducer activity | 6.27803885496668 | bayes_pls_golite062009 |
| protein kinase activity | 2.91563392647119 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.4588656102875 | bayes_pls_golite062009 |
| kinase activity | 2.26401916756851 | bayes_pls_golite062009 |
| transcription regulator activity | 2.23448171655589 | bayes_pls_golite062009 |
| binding | 1.92400975854452 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.64567362100773 | bayes_pls_golite062009 |
| protein histidine kinase activity | 1.60632989169905 | bayes_pls_golite062009 |
| two-component sensor activity | 1.58303578136745 | bayes_pls_golite062009 |
| DNA binding | 1.58172125522651 | bayes_pls_golite062009 |
| nucleic acid binding | 1.56306133971215 | bayes_pls_golite062009 |
| phosphotransferase activity, nitrogenous group as acceptor | 1.45748315828993 | bayes_pls_golite062009 |
| receptor activity | 1.17008073803454 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.10773580590429 | bayes_pls_golite062009 |
| transcription factor activity | 0.970571914515176 | bayes_pls_golite062009 |
| transferase activity | 0.626277634156636 | bayes_pls_golite062009 |
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Region A: Residues: [940-1085] |
1 11 21 31 41 51
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1 PFEDEFNPES RKNRRVKFSV AKSIKSRQST SSVATPATNR SSLTNDVLPE VRSKGKHETK 60
61 DVGNPNMGRE EKNDNGGLEQ LQEKNIKPSI CLTGAEVNEQ NSLSSKHRSR HEGLGSVNLD 120
121 RPFLQSTGTA TSSRNIPTVK DDDKNE
|
| Detection Method: | |
| Confidence: | 13.69897 |
| Match: | 1qkkA_ |
| Description: | Transcriptional regulatory protein DctD, receiver domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| two-component response regulator activity | 6.41182973389827 | bayes_pls_golite062009 |
| molecular transducer activity | 6.27803885496668 | bayes_pls_golite062009 |
| signal transducer activity | 6.27803885496668 | bayes_pls_golite062009 |
| protein kinase activity | 2.91563392647119 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.4588656102875 | bayes_pls_golite062009 |
| kinase activity | 2.26401916756851 | bayes_pls_golite062009 |
| transcription regulator activity | 2.23448171655589 | bayes_pls_golite062009 |
| binding | 1.92400975854452 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.64567362100773 | bayes_pls_golite062009 |
| protein histidine kinase activity | 1.60632989169905 | bayes_pls_golite062009 |
| two-component sensor activity | 1.58303578136745 | bayes_pls_golite062009 |
| DNA binding | 1.58172125522651 | bayes_pls_golite062009 |
| nucleic acid binding | 1.56306133971215 | bayes_pls_golite062009 |
| phosphotransferase activity, nitrogenous group as acceptor | 1.45748315828993 | bayes_pls_golite062009 |
| receptor activity | 1.17008073803454 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.10773580590429 | bayes_pls_golite062009 |
| transcription factor activity | 0.970571914515176 | bayes_pls_golite062009 |
| transferase activity | 0.626277634156636 | bayes_pls_golite062009 |
|
Region A: Residues: [1086-1220] |
1 11 21 31 41 51
| | | | | |
1 TSVKILVVED NHVNQEVIKR MLNLEGIENI ELACDGQEAF DKVKELTSKG ENYNMIFMDV 60
61 QMPKVDGLLS TKMIRRDLGY TSPIVALTAF ADDSNIKECL ESGMNGFLSK PIKRPKLKTI 120
121 LTEFCAAYQG KKNNK
|
| Detection Method: | |
| Confidence: | 123.156545 |
| Match: | 1udrA_ |
| Description: | CheY protein |
Matching Structure (courtesy of the PDB): |
|
