YRC Public Data Repository - Protein Structure Prediction

Protein:	GAT3
Organism:	Saccharomyces cerevisiae
Length:	141 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAT3.

Description	E-value	Query Range	Subject Range
gi\|151941181 - gi\|151941181\|gb\|EDN59559.1\| conserved protein [Saccharomyces cerevisiae YJM789] GAT3 - Protein containing GATA family zinc finger motifs gi\|190406054 - gi\|190406054\|gb\|EDV09321.1\| protein GAT3 [Saccharomyces cerevisiae RM11-1a] GAT3_YEAST - Protein GAT3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAT3 PE=3 SV=1	8.0E-28	[1..141]	[1..141]
pnr-PA - The gene pannier is referred to in FlyBase by the symbol Dmel\pnr (CG3978, FBgn0003117). It is a pro...	2.0E-23	[4..136]	[141..284]
gi\|31982351, gi\|... - gi\|31982351\|ref\|NP_032116.3\| GATA binding protein 2 [Mus musculus], gi\|12835796\|dbj\|BAB23365.1\| unna...	6.0E-23	[8..127]	[279..398]
GATA2 - GATA binding protein 2	9.0E-23	[8..127]	[279..398]
GATA2_RAT - Endothelial transcription factor GATA-2 OS=Rattus norvegicus GN=Gata2 PE=1 SV=1	2.0E-22	[8..127]	[279..398]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIKTLCHPE YKRISVESLL NPVEETIDCE KPHSQTKINT AKPISASLYV TTNNTAVVQH  60
   61 NVQKRKGVTR RCPQCAVIKT SPQWREGPDG EVTLCNACGL FYRKIFLVFG KDLAKRYFNE 120
  121 IKGVSVKRKV PKSLYGVTRT R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.0
Match:	4gatA_
Description:	Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.00967542385368	bayes_pls_golite062009
binding	3.48726415487797	bayes_pls_golite062009
DNA binding	3.36252792779457	bayes_pls_golite062009
nucleic acid binding	3.05528938535257	bayes_pls_golite062009
transcription factor activity	2.70303114587416	bayes_pls_golite062009
transcription activator activity	1.62405765585032	bayes_pls_golite062009
sequence-specific DNA binding	1.5397618957429	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.50210964370113	bayes_pls_golite062009
transcription factor binding	1.38523780690867	bayes_pls_golite062009
ligand-dependent nuclear receptor activity	1.37025623768659	bayes_pls_golite062009
protein binding	1.19451874907667	bayes_pls_golite062009
transcription cofactor activity	0.58115018700114	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.57492522309817	bayes_pls_golite062009
transcription repressor activity	0.256420113528322	bayes_pls_golite062009
catalytic activity	0.101795606736461	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: