| Protein: | YLR035C-A |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1155 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR035C-A.
| Description | E-value | Query Range |
Subject Range |
|
|
746.0 | [0..1] | [1155..174] |
|
Region A: Residues: [1-367] |
1 11 21 31 41 51
| | | | | |
1 MLAHANAQTI RYSLKNNTIT YFNESDVDWS SAIDYQCPDC LIGKSTKHRH IKGSRLKYQN 60
61 SYEPFQYLHT DIFGPVHNLP KSAPSYFISF TDETTKFRWV YPLHDRREDS ILDVFTTILA 120
121 FIKNQFQASV LVIQMDRGSE YTNRTLHKFL EKNGITPCYT TTADSRAHGV AERLNRTLLD 180
181 DCRTQLQCSG LPNHLWFSAI EFSTIVRNSL ASPKSKKSAR QHAGLAGLDI STLLPFGQPV 240
241 IVNDHNPNSK IHPRGIPGYA LHPSRNSYGY IIYLPSLKKT VDTTNYVILQ GKESRLDQFN 300
301 YDALTFDEDL NRLTASYQSF IASNEIQQSD DLNIESDHDF QSDIELHPEQ PRNVLSKAVS 360
361 PTDSTPP
|
| Detection Method: |  |
| Confidence: | 26.0 |
| Match: | 1k6yA |
| Description: | N-terminal Zn binding domain of HIV integrase; Retroviral integrase, catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nuclease activity | 1.94987701094917 | bayes_pls_golite062009 |
| ribonuclease activity | 0.969438660919194 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.787213833707638 | bayes_pls_golite062009 |
| exonuclease activity | 0.738049151007118 | bayes_pls_golite062009 |
| catalytic activity | 0.709734459150736 | bayes_pls_golite062009 |
| 3'-5' exonuclease activity | 0.332143782945747 | bayes_pls_golite062009 |
| hydrolase activity | 0.301910249637397 | bayes_pls_golite062009 |
| binding | 0.205040227344888 | bayes_pls_golite062009 |
|
Region A: Residues: [368-629] |
1 11 21 31 41 51
| | | | | |
1 STHTEDSKRV SKTNIRAPRE VDPNISESNI LPSKKRSSTP QISDIESTGS GGMHRLDVPL 60
61 LAPMSQSNTH ESSHASKSKD FRHSDSYSDN ETNHTNVPIS STGGTNNKTV PQTSEQETEK 120
121 RIIHRSPSID TSSSESNSLH HVVPIKTSDT CPKENTEESI IADLPLPDLP PEPPTELSDS 180
181 FKELPPINSH QTNSSLGGIG DSNAYTTINS KKRSLEDNET EIKVSRDTWN TKNMRSLEPP 240
241 RSKKRIHLIA AVKAVKSIKP IR
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [630-1155] |
1 11 21 31 41 51
| | | | | |
1 TTLRYDEAIT YNKDIKEKEK YIQAYHKEVN QLLKMKTWDT DRYYDRKEID PKRVINSMFI 60
61 FNRKRGGTHK ARFVARGDIQ HPDTYDPGMQ SNTVHHYALM TSLSLASDNN YYITQLDISS 120
121 AYLYADIKEE LYIRPPPHLG MNDKLIRLKK SLYGLKQSGA NWYETIKSYL IKQCGMEEVR 180
181 GWSCVFKNSQ VTICLFVDDM ILFSKDLNAN KKIITTLKKQ YDTKIINLGE SDNEIQYDIL 240
241 GLEIKYQRGK YMKLGMENSL TEKIPKLNVP LNPKGRKLSA PGQPGLYIDQ QELELEEDDY 300
301 KMKVHEMQKL IGLASYVGYK FRFDLLYYIN TLAQHILFPS KQVLDMTYEL IQFIWNTRDK 360
361 QLIWHKSKPV KPTNKLVVIS DASYGNQPYY KSQIGNIYLL NGKVIGGKST KASLTCTSTT 420
421 EAEIHAISES VPLLNNLSHL VQELNKKPIT KGLLTDSKST ISIIISNNEE KFRNRFFGTK 480
481 AMRLRDEVSG NHLHVCYIET KKNIADVMTK PLPIKTFKLL TNKWIH
|
| Detection Method: | |
| Confidence: | 1.41 |
| Match: | 1mu2A |
| Description: | HIV RNase H (Domain of reverse transcriptase); HIV-1 reverse transcriptase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleotidyltransferase activity | 1.61389461562101 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.895925817051023 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.71944542861368 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.710149896697621 | bayes_pls_golite062009 |
| binding | 0.698775322116598 | bayes_pls_golite062009 |
| ribonuclease activity | 0.519152306822884 | bayes_pls_golite062009 |
| catalytic activity | 0.443190761359386 | bayes_pls_golite062009 |
| transferase activity | 0.343279650271418 | bayes_pls_golite062009 |
| nucleic acid binding | 0.0241260721327641 | bayes_pls_golite062009 |
