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View Structure Prediction Details

Protein: GIS4
Organism: Saccharomyces cerevisiae
Length: 774 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GIS4.

Description E-value Query
Range
Subject
Range
gi|151946156 - gi|151946156|gb|EDN64387.1| CAAX box containing protein [Saccharomyces cerevisiae YJM789]
GIS4 - CAAX box containing protein of unknown function, proposed to be involved in the RAS/cAMP signaling p...
GIS4_YEAST - Protein GIS4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GIS4 PE=1 SV=1
0.0 [1..774] [1..774]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.002 [88..384] [993..1286]

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Predicted Domain #1
Region A:
Residues: [1-774]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKSVRVGDY FDNDDNGLWS WYLTNLRLGD FEELIGNQLK YTLLKRFLNS HFYGDNNISA  60
   61 RPNKKILLVS IPENVHEDIS ILEIFLKDYF HLEKLEHIQI SKLTHSHCYN HENHYLLTDN 120
  121 LNNFQDPTFL EFASTSWQVQ KNSKALNNNN RNSIPPPTIS SSKASNGKLE SNVSDDQWSN 180
  181 INTQTSTATR TNTNTRTLTS PDTVDINVTS VNSQSNNNDT PQDNENEVDE EDATSSIVLN 240
  241 FSHSRTVDSK PNRLPKIFPS YTNEDYTPSH SEIMSIDSFA GEDVSSTYPG QDLSLTTARR 300
  301 EDESGQDEVE DHYSRVSHDL GDESIDQASY SMESSVSYTS YSSSSNSSSA HYSLSSSSRG 360
  361 NPKRENIDHT NATYVSELSS ITSSIDNLTT STTPEEEDNL IHHNYDAQGY GSGEDDGEEV 420
  421 YDDEDLSSSD YSVLSILPSI SICDSLGYFR LVLQSILIQD PDTKEIFTAI RQSNNKPTMA 480
  481 SVTDDWLLYD SNFSMNNLQI LTLQDLLDIK RSFPKILFYT MVIVTNSGKQ VEEEFKNPNY 540
  541 DNREGISKEQ PLDSELSLTN DPQQYFPTAY NNGYNDYIDD EDDEDDGDDA SLSEQSGPQM 600
  601 YIPTRMESNV TTAHRSIRTV NSIGEWAFNR HNSVTKIDKS NSNELDNSKT GESTVLSSEP 660
  661 HPMTQLSNSN TTSSNFSHSL KTKNSHKPNS KGNNESNSKN ELKKIKSSIN AMSAVERSKS 720
  721 LPLPTLLKSL SGIDNPTHAT NKDRKRWKFQ MNRFKNHKNS GSAGTDKSQR CAIM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [135-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSWQVQKNSK ALNNNNRNSI PPPTISSSKA SNGKLESNVS DDQWSNINTQ TSTATRTNTN  60
   61 TRTLTSPDTV DINVTSVNSQ SNNNDTPQDN ENEVDEEDAT SSIVLNFSHS RTVDSKPNRL 120
  121 PKIFPSYTNE DYTPSHSEIM SIDSFAGEDV SSTYPGQDLS LTTARREDES GQDEVEDHYS 180
  181 RVSHDLGDES IDQASYSMES SVSYTSYSSS SNSSSAHYSL SSSSRGNPKR ENIDHTNATY 240
  241 VSELSSITSS IDNLT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [390-536]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSTTPEEEDN LIHHNYDAQG YGSGEDDGEE VYDDEDLSSS DYSVLSILPS ISICDSLGYF  60
   61 RLVLQSILIQ DPDTKEIFTA IRQSNNKPTM ASVTDDWLLY DSNFSMNNLQ ILTLQDLLDI 120
  121 KRSFPKILFY TMVIVTNSGK QVEEEFK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [537-774]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPNYDNREGI SKEQPLDSEL SLTNDPQQYF PTAYNNGYND YIDDEDDEDD GDDASLSEQS  60
   61 GPQMYIPTRM ESNVTTAHRS IRTVNSIGEW AFNRHNSVTK IDKSNSNELD NSKTGESTVL 120
  121 SSEPHPMTQL SNSNTTSSNF SHSLKTKNSH KPNSKGNNES NSKNELKKIK SSINAMSAVE 180
  181 RSKSLPLPTL LKSLSGIDNP THATNKDRKR WKFQMNRFKN HKNSGSAGTD KSQRCAIM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle