| Protein: | KAR5 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 504 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KAR5.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..504] | [1..504] |
|
|
3.0E-98 | [6..277] | [12..277] |
|
|
3.0E-93 | [31..277] | [4..243] |
|
Region A: Residues: [1-108] |
1 11 21 31 41 51
| | | | | |
1 MFEMRYVYLF AICIKFVSSS ELGKINNLLQ GRLIYTDNSV ATNVLESKFP FLKSTCVKDA 60
61 LKLFLPQCIA NGLESIDAET RVETAIKLSI CEFQASGLGE IPENCMVD
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.631 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.646 | a.7.1 | Spectrin repeat |
| View | Download | 0.633 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.695 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.695 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.646 | a.7.1 | Spectrin repeat |
| View | Download | 0.636 | a.7.1 | Spectrin repeat |
| View | Download | 0.636 | a.7.1 | Spectrin repeat |
| View | Download | 0.633 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.631 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.608 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.592 | a.4.1 | Homeodomain-like |
| View | Download | 0.583 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.524 | a.66.1 | Transducin (alpha subunit), insertion domain |
| View | Download | 0.518 | a.39.1 | EF-hand |
| View | Download | 0.509 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.507 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.503 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.498 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.489 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.480 | a.7.1 | Spectrin repeat |
| View | Download | 0.478 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.477 | a.29.2 | Bromodomain |
| View | Download | 0.466 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.465 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.457 | d.34.1 | DNA-binding domain of Mlu1-box binding protein MBP1 |
| View | Download | 0.444 | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.436 | a.7.1 | Spectrin repeat |
| View | Download | 0.433 | a.39.2 | Insect pheromon/odorant-binding proteins |
| View | Download | 0.429 | a.7.7 | BAG domain |
| View | Download | 0.429 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.417 | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.416 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.415 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.409 | a.130.1 | Chorismate mutase II |
| View | Download | 0.404 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.403 | a.39.1 | EF-hand |
| View | Download | 0.400 | d.74.3 | RBP11-like subunits of RNA polymerase |
| View | Download | 0.398 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.391 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.384 | a.4.1 | Homeodomain-like |
| View | Download | 0.381 | a.77.1 | DEATH domain |
| View | Download | 0.377 | a.112.1 | Description not found. |
| View | Download | 0.376 | a.7.1 | Spectrin repeat |
| View | Download | 0.372 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.367 | a.29.2 | Bromodomain |
| View | Download | 0.366 | c.23.12 | Formate/glycerate dehydrogenase catalytic domain-like |
| View | Download | 0.360 | a.47.2 | t-snare proteins |
| View | Download | 0.359 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.356 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.350 | a.7.1 | Spectrin repeat |
| View | Download | 0.348 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.344 | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.340 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.336 | b.82.3 | cAMP-binding domain-like |
| View | Download | 0.335 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.329 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.326 | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.323 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.320 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.316 | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.312 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.311 | g.53.1 | TAZ domain |
| View | Download | 0.304 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.302 | a.77.1 | DEATH domain |
| View | Download | 0.301 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.301 | a.1.1 | Globin-like |
| View | Download | 0.291 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.289 | d.110.4 | SNARE-like |
| View | Download | 0.289 | a.77.1 | DEATH domain |
| View | Download | 0.288 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.287 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.279 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.278 | d.110.4 | SNARE-like |
| View | Download | 0.275 | f.32.1 | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.275 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.271 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.269 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.268 | d.110.4 | SNARE-like |
| View | Download | 0.261 | a.26.1 | 4-helical cytokines |
| View | Download | 0.256 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.255 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.253 | a.26.1 | 4-helical cytokines |
| View | Download | 0.253 | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.251 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.246 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.246 | a.26.1 | 4-helical cytokines |
| View | Download | 0.246 | a.22.1 | Histone-fold |
| View | Download | 0.245 | a.29.2 | Bromodomain |
| View | Download | 0.243 | a.1.1 | Globin-like |
| View | Download | 0.240 | c.95.1 | Thiolase-like |
| View | Download | 0.235 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.234 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.233 | a.21.1 | HMG-box |
| View | Download | 0.230 | a.7.1 | Spectrin repeat |
| View | Download | 0.225 | a.77.1 | DEATH domain |
| View | Download | 0.223 | a.47.2 | t-snare proteins |
| View | Download | 0.222 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.222 | d.15.1 | Ubiquitin-like |
| View | Download | 0.220 | a.46.1 | Methionine synthase domain |
| View | Download | 0.220 | d.64.1 | eIF1-like |
| View | Download | 0.217 | a.152.1 | Antioxidant defence protein AhpD |
| View | Download | 0.216 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.215 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.214 | a.24.3 | Cytochromes |
| View | Download | 0.214 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.211 | a.28.1 | ACP-like |
| View | Download | 0.210 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.207 | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.207 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.207 | a.19.1 | Fertilization protein |
| View | Download | 0.204 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.201 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.200 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
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Region A: Residues: [109-205] |
1 11 21 31 41 51
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1 DLGSMMDCMF ELESSSQWWT TYSGNYQRLS SICYENLLPF EKEQILKLFL NITELYDSFG 60
61 DDVDTKLNHL MFQMEQDSQN FLDDLARMFR NYDNELR
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Region B: Residues: [248-344] |
1 11 21 31 41 51
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1 LMNEVDTVHH IMSDLADELA KNDIKSKIND LKDDSLNNLQ DLVEMSNDVK EYYSRNNKLV 60
61 NTELENFSMG LKKQLGGMSK DLSESQMEAI ELLQGFN
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Region C: Residues: [408-504] |
1 11 21 31 41 51
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1 KKLDDIEIRV SLVHKNVMTM MRVLDFMWKT SKMIIRCGYL AVKNKYYWLL CSVVWIWSKY 60
61 RTSRVNVKMI PIKRYYQWAA LLLSIYLGAK TGSLIDF
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| Detection Method: | |
| Confidence: | 7.42 |
| Match: | 3btaA |
| Description: | Botulinum neurotoxin |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [206-247] |
1 11 21 31 41 51
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1 NATESNRIIL ENDLSFFRNK VNDVLYETSE QLEVQIIEKN SQ
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Region B: Residues: [345-407] |
1 11 21 31 41 51
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1 SILHDSLLPS MTDEIVPEMT NFKNTLLQEW TAITSTLNGD FALWNEEIFS TFNDISEKLN 60
61 GTK
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| Detection Method: | |
| Confidence: | 7.42 |
| Match: | 3btaA |
| Description: | Botulinum neurotoxin |
| Matching Structure (courtesy of the PDB): |
|
