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View Structure Prediction Details

Protein: AIP1
Organism: Saccharomyces cerevisiae
Length: 615 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AIP1.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [2..614] [894..1483]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
0.0 [10..509] [823..1314]

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Predicted Domain #1
Region A:
Residues: [1-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSISLKEII PPQPSTQRNF TTHLSYDPTT NAIAYPCGKS AFVRCLDDGD SKVPPVVQFT  60
   61 GHGSSVVTTV KFSPIKGSQY LCSGDESGKV IVWGWTFDKE SNSVEVNVKS EFQVLAGPIS 120
  121 DISWDFEGRR LCVVGEGRDN FGVFISWDSG NSLGEVSGHS QRINACHLKQ SRPMRSMTVG 180
  181 DDGSVVFYQG PPFKFSASDR THHKQGSFVR DVEFSPDSGE FVITVGSDRK ISCFDGKSGE 240
  241 FLKYIED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 105.519517
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.86142918698875 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
binding 2.22722319261713 bayes_pls_golite062009
actin filament binding 2.0735069176589 bayes_pls_golite062009
myosin heavy chain kinase activity 1.24520283111044 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.22384651674093 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 1.14494479608652 bayes_pls_golite062009
protein binding 1.11897341394404 bayes_pls_golite062009
myosin binding 0.989691178611801 bayes_pls_golite062009
tubulin binding 0.968047176592527 bayes_pls_golite062009
0.92526678064403 bayes_pls_golite062009
microtubule binding 0.834073483714259 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
nucleic acid binding 0.438994634856101 bayes_pls_golite062009
dynein binding 0.41765917405931 bayes_pls_golite062009
transcription regulator activity 0.415449383711249 bayes_pls_golite062009
snoRNA binding 0.347797037104681 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
myosin II binding 0.0145748031956598 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [248-366]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQEPVQGGIF ALSWLDSQKF ATVGADATIR VWDVTTSKCV QKWTLDKQQL GNQQVGVVAT  60
   61 GNGRIISLSL DGTLNFYELG HDEVLKTISG HNKGITALTV NPLISGSYDG RIMEWSSSS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.32
Match: 1jjuB
Description: Quinohemoprotein amine dehydrogenase B chain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [367-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHQDHSNLIV SLDNSKAQEY SSISWDDTLK VNGITKHEFG SQPKVASANN DGFTAVLTND  60
   61 DDLLILQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.0
Match: 1gxrA_
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [434-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFTGDIIKSV RLNSPGSAVS LSQNYVAVGL EEGNTIQVFK LSDLEVSFDL KTPLRAKPSY  60
   61 ISISPSETYI AAGDV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1c5kA_
Description: TolB, C-terminal domain; TolB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [509-615]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKILLYDLQ SREVKTSRWA FHTSKINAIS WKPAEKGANE EEIEEDLVAT GSLDTNIFIY  60
   61 SVKRPMKIIK ALNAHKDGVN NLLWETPSTL VSSGADACIK RWNVVLE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.77
Match: 1k8kC
Description: Arp2/3 complex 41 kDa subunit ARPC1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle