YRC Public Data Repository - Protein Structure Prediction

Protein:	APP1
Organism:	Saccharomyces cerevisiae
Length:	587 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APP1.

Description	E-value	Query Range	Subject Range
gi\|151944441 - gi\|151944441\|gb\|EDN62719.1\| actin patch protein [Saccharomyces cerevisiae YJM789] APP1 - Protein of unknown function, interacts with Rvs161p and Rvs167p; computational analysis of protein-p... APP1_YEAST - Phosphatidate phosphatase APP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APP1 PE=1...	0.0	[1..587]	[1..587]
SPBC29B5.04c - conserved fungal protein YNK4_SCHPO - Uncharacterized protein C29B5.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC29B5...	0.0	[187..494]	[195..501]
gi\|1827509 - gi\|1827509\|dbj\|BAA12197.1\| unnamed protein product [Schizosaccharomyces pombe]	0.0	[187..494]	[195..501]
gi\|19553454, gi\|... - gi\|21325028\|dbj\|BAB99650.1\| Hypothetical protein [Corynebacterium glutamicum ATCC 13032], gi\|1955345...	9.0E-83	[197..428]	[77..298]
gi\|7471663 - pir\|\|G75425 conserved hypothetical protein - Deinococcus radiodurans (strain R1) gi\|15806211, gi\|... - gi\|6458933\|gb\|AAF10764.1\|AE001968_3 conserved hypothetical protein [Deinococcus radiodurans R1], gi\|...	6.0E-63	[269..433]	[151..314]

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Predicted Domain #1

Region A:
Residues: [1-159]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSQGYDESS SSTAATSGPT SGDPRMGKKQ RFMNLIRTTK DVYIPNLTSS ISQKTMDGIR  60
   61 STTNSFEGYN DLPMELPHNT TITYFPTYTT TNLVDPDGLS APRKDFETTV RCAVSYPGNP 120
  121 TSRRNRWLLS LCKQYLRTGT AEADVAPVVP PHLEEDSGD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [160-474]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNDSQSSIES SLSSKSENRY SHMGIQEEDV LNERIQGFLS KKVPNTPVVV DLLPKDKLRG  60
   61 DTASFFGTTD SYGNLLIKAE TDFLPSKINI TLDTPIEGHA DPISETFPAN YVSPYGIGLI 120
  121 SDIDDTIKHT GVTGDRRSMF RNVFIHDVQS WVIDGVPLWY KTLHDVADVD FFYVSNSPIQ 180
  181 TFTLLKQYIC ANFPPGPIFL KQYSGNFFST IMTSSANRKI QPIANILKDF PKKKFILVGD 240
  241 SGEHDLEAYT TTALQFPNQI LAIYIRCCSN SMSDVPSHDE EVMNEVNNII ELQQRPMQMT 300
  301 KSTVRTRRRP PPPPI

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [475-587]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSTQKPSLTE EQTESIRMSR RNKDENNAKR VAPPPLPNRQ LPNLDANTYY VPSSQNDYGM  60
   61 YGAFMDKKAD EWKRRVMDSI QKLSNQDTTL MFFSDPALSL EDSIRRIREK YSN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits