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View Structure Prediction Details

Protein: UBP2
Organism: Saccharomyces cerevisiae
Length: 1272 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBP2.

Description E-value Query
Range
Subject
Range
UBP2_YEAST - Ubiquitin carboxyl-terminal hydrolase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
UBP2 - Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; interacts with Rsp5p...
0.0 [1..1272] [1..1272]
UBP2_KLULA - Ubiquitin carboxyl-terminal hydrolase 2 OS=Kluyveromyces lactis GN=UBP2 PE=3 SV=2
UBP2_KLULA - Ubiquitin carboxyl-terminal hydrolase 2 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 7...
0.0 [26..1272] [12..1218]
ubp2 - ubiquitin C-terminal hydrolase Ubp2
UBP2_SCHPO - Probable ubiquitin carboxyl-terminal hydrolase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 248...
0.0 [442..1270] [324..1136]
USP25 - ubiquitin specific peptidase 25
4.0E-51 [686..1256] [117..655]
gi|15030172 - gi|15030172|gb|AAH11341.1| Usp4 protein [Mus musculus]
2.0E-47 [627..938] [161..429]

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Predicted Domain #1
Region A:
Residues: [1-616]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNEDNELQK AIENHHNQLL NQDKENADRN GSVIEDLPLY GTSINQQSTP GDVDDGKHLL  60
   61 YPDIATNLPL KTSDRLLDDI LCDTIFLNST DPKVMQKGLQ SRGILKESML SYSTFRSSIR 120
  121 PNCLGSLTDQ VVFQTKSEYD SISCPKYNKI HVFQAVIFNP SLAEQQISTF DDIVKIPIYH 180
  181 LKVSVKVRQE LERLKKHVGV TQFHSLDHLH EYDRVDLSTF DSSDPNLLDY GIYVSDDTNK 240
  241 LILIEIFKPE FNSPEEHESF TADAIKKRYN AMCVKNESLD KSETPSQVDC FYTLFKIFKG 300
  301 PLTRKSKAEP TKTIDSGNLA LNTHLNPEWL TSKYGFQASS EIDEETNEIF TEYVPPDMVD 360
  361 YVNDLETRKI RESFVRKCLQ LIFWGQLSTS LLAPNSPLKN TKSVKGMSSL QTSFSTLPWF 420
  421 HLLGESRARI LLNSNEQTHS PLDAEPHFIN LSVSHYYTDR DIIRNYESLS SLDPENIGLY 480
  481 FDALTYIANR KGAYQLIAYC GKQDIIGQEA LENALLMFKI NPKECNISEL NEATLLSIYK 540
  541 YETSNKSQVT SNHLTNLKNA LRLLAKYTKS DKLKFYVDHE PYRALSQAYD TLSIDESVDE 600
  601 DIIKTAYSVK INDSPG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [617-722]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKLDCDRALY TIAISKRSLD LFNFLTEECP QFSNYYGPEK LDYQEALKLL QVNENASDET  60
   61 ILKIFKQKWF DENVYEPDQF LILRAALTKI SIERNSTLIT NFLLTG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.893 0.067 protein deubiquitination a.118.9 ENTH/VHS domain

Predicted Domain #3
Region A:
Residues: [723-786]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIDPNSLPPE NWPTGINNIG NTCYLNSLLQ YYFSIAPLRR YVLEYQKTVE NFNDHLSNSG  60
   61 HIRR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 13.69897
Match: PF00442
Description: No description for PF00442 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [787-838]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGGREISRGE VERSIQFIYQ LRNLFYAMVH TRERCVTPSK ELAYLAFAPS NV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [839-1184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVEFEVEGNK VVDQTGVLSD SKKETTDDAF TTKIKDTSLI DLEMEDGLNG DVGTDANRKK  60
   61 NESNDAEVSE NEDTTGLTSP TRVAKISSDQ LENALEMGRQ QDVTECIGNV LFQIESGSEP 120
  121 IRYDEDNEQY DLVKQLFYGT TKQSIVPLSA TNKVRTKVER FLSLLINIGD HPKDIYDAFD 180
  181 SYFKDEYLTM EEYGDVIRTV AVTTFPTILQ VQIQRVYYDR ERLMPFKSIE PLPFKEVIYM 240
  241 DRYADTENPL LLAKKKETEE MKQKLKVMKN RQRELLSRDD SGLTRKDAFL ESIKLLESDT 300
  301 IKKTPLKIEA ANDVIKTLRN NVQNIDNELM KLYNDINSLE EKISHQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1185-1272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDDFKEYGYS LFSVFIHRGE ASYGHYWIYI KDRNRNGIWR KYNDETISEV QEEEVFNFNE  60
   61 GNTATPYFLV YVKQGQEGDI EPLKRILK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 23.886057
Match: PF00443
Description: Ubiquitin carboxyl-terminal hydrolase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1152-1272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VIKTLRNNVQ NIDNELMKLY NDINSLEEKI SHQFDDFKEY GYSLFSVFIH RGEASYGHYW  60
   61 IYIKDRNRNG IWRKYNDETI SEVQEEEVFN FNEGNTATPY FLVYVKQGQE GDIEPLKRIL 120
  121 K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.0
Match: 2aynA
Description: Structure of USP14, a proteasome-associated deubiquitinating enzyme
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle