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View Structure Prediction Details

Protein: SVL3
Organism: Saccharomyces cerevisiae
Length: 825 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SVL3.

Description E-value Query
Range
Subject
Range
SVL3 - Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green ...
SVL3_YEAST - Styryl dye vacuolar localization protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
0.0 [1..817] [1..817]
CTTNBP2 - cortactin binding protein 2
0.0 [261..761] [53..538]
gi|3608372 - gi|3608372|gb|AAC35911.1| brain specific cortactin-binding protein CBP90 [Rattus norvegicus]
9.0E-67 [230..761] [12..535]
gi|27378258, gi|... - gi|27378258|ref|NP_769787.1| 2-dehydropantoate 2-reductase [Bradyrhizobium japonicum USDA 110], gi|2...
5.0E-62 [6..342] [1..321]
gi|186468796, gi... - gi|23128042|ref|ZP_00109898.1| COG1893: Ketopantoate reductase [Nostoc punctiforme PCC 73102], gi|18...
1.0E-61 [6..339] [1..319]

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Predicted Domain #1
Region A:
Residues: [1-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSLRVLA IGNNPNILFY TSRFQLAKNI DLYHVNDSKS CQFEIETEYY GKDRFELENH  60
   61 FTSIEHLTEA LSSKSSEAVF DIIIMSAPSL QELSSLASKL TSIIDSNTKI FLESSGFIQL 120
  121 EPFVKLSMES PHVNVFSILT DLDIRQIGPN HFKHFPSTAK ENTIYLGESK SSTEKYSSGV 180
  181 ITLLTTFEKL FAKLFSNIKI NLCNFSSIEF LSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.221849
Match: 1ks9A_
Description: Ketopantoate reductase PanE
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [214-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QWKLAISRIC FDPLLIMFEQ ENPSDLDQQI IAKPLISGLV TEIITVAKTM GARLNSSHDN  60
   61 ENSLLSLWKN SYHSTNKPPA LVYHFIHQTT PLNIDILLLQ TILLADDFGI KTPYLEFLYS 120
  121 VLSQFERLNS GK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.221849
Match: 1ks9A_
Description: Ketopantoate reductase PanE
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [346-550]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKWFIRSDEK TQILQSLQKS QKNESALQTQ ITSLQGQISK LRQELLMQAK QHEMETNELK  60
   61 EKHQVALKAQ AQAQAQAQSQ AQTSIEALTP TEATNQSDTN EYKATGTPNL RDIEDMALYS 120
  121 VNYGDSPVRS PPPVVSSQPQ MNSPLSSHSQ TFGENNGTND KLLQERELQL RKKELELQER 180
  181 ELEFQKRALQ QQRFNNSNNS IPRKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [551-825]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFPQLQQSAN VRSNSRGMHG TNGAMSQPAS AGNFVDPISS SIAAYDPQQP PSLPLQQPQQ  60
   61 SVQVQPFHSH SIKPTSRKNR NSNMPNIGNP SSINMSDFGR PPNNSSQTRL NSMPTHSIVN 120
  121 QNRLRSQQSK NKLNMPHATN PNNTFNQVPA PSLNNHVPTQ RQFSSSTMIE VTNNNNKVNN 180
  181 SSSNPDISTN SVVHNAMQFT NTNNNTSSTV DINDPKNIAP PPTTSVSAPS TPTLSSSSQM 240
  241 ANMASPSTDN GDNEEKNGGK KKRFGLFKKK NKSKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle