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View Structure Prediction Details

Protein: PML39
Organism: Saccharomyces cerevisiae
Length: 334 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PML39.

Description E-value Query
Range
Subject
Range
PML39 - Protein required for nuclear retention of unspliced pre-mRNAs along with Mlp1p and Pml1p; anchored t...
719.0 [0..1] [334..53]
gi|49527305 - gi|49527305|emb|CAG60945.1| unnamed protein product [Candida glabrata]
gi|50291123, gi|... - gi|50291123|ref|XP_447994.1| unnamed protein product [Candida glabrata], gi|49527305|emb|CAG60945.1|...
102.0 [0..6] [334..9]
gi|49642285 - gi|49642285|emb|CAH00247.1| KLLA0D01881p [Kluyveromyces lactis]
gi|50306355, gi|... - gi|50306355|ref|XP_453151.1| unnamed protein product [Kluyveromyces lactis], gi|49642285|emb|CAH0024...
74.0 [0..6] [308..5]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKDALEVRL KSIRHSLDKN TKLLPGKYRN TLGERLITKW RYKKKSHNGS SMLPEKCKSH  60
   61 VQLYDDLVQE SSKHFVGFRL HDLRALLKRI CSIQNYTRHV LIEWDVRWVN PLTLASKGWE 120
  121 PYQSASQSQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.895 a.29.12 Description not found.

Predicted Domain #2
Region A:
Residues: [130-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPFKCCCCHA IMTIPLLKNG DDVADYTMKL NEKIWNSNII GNHLQKCPWR ENQVDLNKEY  60
   61 YLSSQNLIRE IERIHTEIDR IVSGSNEFSL KRNSSRIFHY LSEKEIQKLA FFFDCKDYSL 120
  121 VGLLLLGYTK FQKDDLVQCT ACFHRASLKK LEYTEFNGHA LWCRYYNKEL LPTMLLELIG 180
  181 KEDKLITKLG VGERLNKLEA VLQTL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.977
Match: 1oxnA
Description: Structure and Function Analysis of Peptide Antagonists of Melanoma Inhibitor of Apoptosis (ML-IAP)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle