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View Structure Prediction Details

Protein: gi|14585877, gi|...
Organism: Homo sapiens
Length: 296 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|14585877, gi|....

Description E-value Query
Range
Subject
Range
FAM86A - family with sequence similarity 86, member A
9.0E-55 [1..296] [1..330]
gi|109127492 - gi|109127492|ref|XP_001100213.1| PREDICTED: similar to CG7889-PA [Macaca mulatta]
3.0E-54 [1..296] [1..330]
EF2KT_MOUSE - Protein-lysine N-methyltransferase EEF2KMT OS=Mus musculus GN=Eef2kmt PE=1 SV=1
1.0E-48 [1..296] [1..329]
gi|149042621, gi... - gi|62655682|ref|XP_220157.3| PREDICTED: similar to CG7889-PA [Rattus norvegicus], gi|157820553|ref|N...
4.0E-48 [1..296] [1..329]
EF2KT_BOVIN - Protein-lysine N-methyltransferase EEF2KMT OS=Bos taurus GN=EEF2KMT PE=2 SV=2
2.0E-42 [1..296] [1..340]

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Predicted Domain #1
Region A:
Residues: [1-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPEENAGTE LLLQSFERRF LAARTLRSFP WQSLEAKLRD SSDSELLRDI LHKTVKHPVC  60
   61 VKHPPSVKYA RCFLSELIKK PSGGSVTLSE STAIISYGTT GLVTWDAALY LAEWAIENPA 120
  121 VFTNRTVLEL GSGAGLTGLA ICKMCRPRAY IFSDCHSRVL EQLRGNVLLN GLSLEADITA 180
  181 KLDSPRVTVA QLDWDVATVH QLSAFQPDVV IAADVLYCPE AIMSLVGVLR RLAACREHQR 240
  241 APEVYVAFTV RNPETCQLFT TELGRAGIRW EVEPRHEQKL FPYEEHLEMA MLNLTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1uwvA
Description: Crystal Structure of RumA, the iron-sulfur cluster containing E. coli 23S Ribosomal RNA 5-Methyluridine Methyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity 0.569065423404044 bayes_pls_golite062009
catalytic activity 0.486907672100804 bayes_pls_golite062009
methyltransferase activity 0.155495931533276 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.145822362574272 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle