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View Structure Prediction Details

Protein: TCEB3
Organism: Homo sapiens
Length: 772 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TCEB3.

Description E-value Query
Range
Subject
Range
gi|108999119 - gi|108999119|ref|XP_001103322.1| PREDICTED: elongin A isoform 1 [Macaca mulatta]
357.0 [0..26] [772..133]
gi|114554661 - gi|114554661|ref|XP_513196.2| PREDICTED: elongin A [Pan troglodytes]
300.0 [0..37] [772..18]
gi|73950625 - gi|73950625|ref|XP_535361.2| PREDICTED: similar to Transcription elongation factor B polypeptide 3 (...
294.0 [0..26] [772..133]
gi|51859136, gi|... - gi|51859136|gb|AAH81815.1| Tceb3 protein [Rattus norvegicus], gi|149024297|gb|EDL80794.1| transcript...
292.0 [0..1] [772..1]
ELOA1_MOUSE - Transcription elongation factor B polypeptide 3 OS=Mus musculus GN=Tceb3 PE=1 SV=3
285.0 [0..1] [772..1]
gi|27462076 - gi|27462076|gb|AAO15305.1|AF116729_1 MSTP059 [Homo sapiens]
274.0 [0..108] [772..1]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAESALQVV EKLQARLAAN PDPKKLLKYL KKLSTLPITV DILAETGVGK TVNSLRKHEH  60
   61 VGSFARDLVA QWKKLVPVER NAEPDEQDFE KSNSRKRPRD ALQKEEEMEG DYQETWKATG 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.221849
Match: 1wjtA
Description: Solution structure of the N-terminal Domain I of mouse transcription elongation factor S-II protein 3
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [121-271]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSYSPDHRQ KKHRKLSELE RPHKVSHGHE RRDERKRCHR MSPTYSSDPE SSDYGHVQSP  60
   61 PSCTSPHQMY VDHYRSLEED QEPIVSHQKP GKGHSNAFQD RLGASQERHL GEPHGKGVVS 120
  121 QNKEHKSSHK DKRPVDAKSD EKASVVSREK S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [272-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKALSKEENR RPPSGDNARE KPPSSGVKKE KDREGSSLKK KCLPPSEAAS DNHLKKPKHR  60
   61 DPEKAKLDKS KQGLDSFDTG KGAGDLLPKV KEKGSNNLKT PEGKVKTNLD RKSLGSLPKV 120
  121 EETDMEDEFE QPTMSFESYL SYDQPRKKKK KIVKTSATAL GDKGLKKNDS KSTGKNLDSV 180
  181 QKLPKVNKTK SEKPAG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [468-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADLAKLRKVP DVLPVLPDLP LPAIQANYRP LPSLELISSF QPKRKAFSSP QEEEEAGFTG  60
   61 RRMNSKMQVY SGSKCAYLPK MMTLHQQCIR VLKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [562-669]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIDSIFEVGG VPYSVLEPVL ERCTPDQLYR IEEYNHVLIE ETDQLWKVHC HRDFKEERPE  60
   61 EYESWREMYL RLQDAREQRL RVLTKNIQFA HANKPKGRQA KMAFVNSV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 86.585027
Match: PF06881.2
Description: No description for PF06881.2 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.799 N/A N/A a.7.11 Description not found.
View Download 0.578 N/A N/A a.7.1 Spectrin repeat
View Download 0.569 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.569 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.517 N/A N/A a.250.1 Description not found.
View Download 0.485 N/A N/A a.243.1 Description not found.
View Download 0.484 N/A N/A a.7.1 Spectrin repeat
View Download 0.462 N/A N/A a.118.8 TPR-like
View Download 0.457 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.445 N/A N/A a.118.8 TPR-like

Predicted Domain #6
Region A:
Residues: [670-772]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKPPRDVRRR QEKFGTGGAA VPEKIKIKPA PYPMGSSHAS ASSISFNPSP EEPAYDGPST  60
   61 SSAHLAPVVS STVSYDPRKP TVKKIAPMMA KTIKAFKNRF SRR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.630 a.29.2 Bromodomain
View Download 0.391 a.29.2 Bromodomain
View Download 0.385 a.29.2 Bromodomain
View Download 0.377 a.29.2 Bromodomain
View Download 0.348 a.29.2 Bromodomain
View Download 0.324 a.24.21 Description not found.
View Download 0.311 a.24.19 Description not found.
View Download 0.309 c.44.1 Phosphotyrosine protein phosphatases I
View Download 0.293 a.7.7 BAG domain
View Download 0.271 a.244.1 Description not found.


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