YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: METTL6
Organism: Homo sapiens
Length: 255 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for METTL6.

Description E-value Query
Range		 Subject
Range
gi|114585570 - gi|114585570|ref|XP_001159583.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
 8.0E-46 [1..255] [1..255]
METL6_MOUSE - Methyltransferase-like protein 6 OS=Mus musculus GN=Mettl6 PE=2 SV=2
 3.0E-44 [1..255] [1..255]
METL6_PONPY - Methyltransferase-like protein 6 - Pongo pygmaeus (Orangutan)
METL6_PONAB - Methyltransferase-like protein 6 OS=Pongo abelii GN=METTL6 PE=2 SV=1
 6.0E-44 [1..255] [1..255]
gi|109050643 - gi|109050643|ref|XP_001082383.1| PREDICTED: similar to methyltransferase like 6 isoform 1 [Macaca mu...
 9.0E-44 [1..255] [1..255]
gi|57103588 - gi|57103588|ref|XP_534257.1| PREDICTED: similar to ZK1058.5 [Canis familiaris]
 3.0E-43 [1..255] [1..254]
METL6_RAT - Methyltransferase-like protein 6 OS=Rattus norvegicus GN=Mettl6 PE=2 SV=1
 2.0E-42 [1..255] [1..255]
gi|115925436, gi... - gi|115925436|ref|XP_001189493.1| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus], gi...
 2.0E-39 [9..255] [14..258]
gi|112419026 - gi|112419026|gb|AAI22481.1| LOC733347 protein [Xenopus laevis]
 7.0E-39 [5..255] [65..315]
gi|68384747 - gi|68384747|ref|XP_697725.1| PREDICTED: hypothetical protein [Danio rerio]
 3.0E-38 [5..255] [19..269]

Back

Predicted Domain #1
Region A:
Residues: [1-255] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLQRKGLQ ARILTSEEEE KLKRDQTLVS DFKQQKLEQE AQKNWDLFYK RNSTNFFKDR  60
   61 HWTTREFEEL RSCREFEDQK LTMLEAGCGV GNCLFPLLEE DPNIFAYACD FSPRAIEYVK 120
  121 QNPLYDTERC KVFQCDLTKD DLLDHVPPES VDVVMLIFVL SAVHPDKMHL VLQNIYKVLK 180
  181 PGKSVLFRDY GLYDHAMLRF KASSKLGENF YVRQDGTRSY FFTDDFLAQL FMDTGYEEVV 240
  241 NEYVFRETVN KKEGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 2fk7A
Description: Crystal structure of Hma (MmaA4) from Mycobacterium tuberculosis, apo-form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity 1.55708326065545 bayes_pls_golite062009
protein methyltransferase activity 0.90417202530863 bayes_pls_golite062009
N-methyltransferase activity 0.89763572661057 bayes_pls_golite062009
binding 0.777596419415505 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.352072576393216 bayes_pls_golite062009
methyltransferase activity 0.349480046648587 bayes_pls_golite062009
histone methyltransferase activity 0.34836765632152 bayes_pls_golite062009
DNA binding 0.07821658818758 bayes_pls_golite062009
transcription regulator activity 0.073128297647348 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle