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View Structure Prediction Details

Protein: REG3G
Organism: Homo sapiens
Length: 175 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for REG3G.

Description E-value Query
Range
Subject
Range
gi|49456831 - gi|49456831|emb|CAG46736.1| UNQ429 [Homo sapiens]
8.0E-39 [1..175] [1..175]
gi|109103573 - gi|109103573|ref|XP_001112492.1| PREDICTED: similar to regenerating islet-derived 3 gamma isoform 3 ...
1.0E-38 [1..175] [1..175]
REG3A_MOUSE - Regenerating islet-derived protein 3-alpha OS=Mus musculus GN=Reg3a PE=1 SV=1
2.0E-38 [1..174] [1..174]
gi|55596997, gi|... - gi|55596997|ref|XP_515572.1| PREDICTED: regenerating islet-derived 1 alpha isoform 6 [Pan troglodyte...
9.0E-37 [5..175] [1..166]
gi|40363429, gi|... - gi|50950147|ref|NP_001002945.1| pancreatitis-associated protein [Canis lupus familiaris], gi|4036342...
2.0E-36 [5..172] [1..168]

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Predicted Domain #1
Region A:
Residues: [1-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPPMALPSV SWMLLSCLIL LCQVQGEETQ KELPSPRISC PKGSKAYGSP CYALFLSPKS  60
   61 WMDADLACQK RPSGKLVSVL SGAEGSFVSS LVRSISNSYS YIWIGLHDPT QGSEPDGDGW 120
  121 EWSSTDVMNY FAWEKNPSTI LNPGHCGSLS RSTGFLKWKD YNCDAKLPYV CKFKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.39794
Match: 1uv0A
Description: Pancreatitis-associated protein 1 from human
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sugar binding 5.35626613750458 bayes_pls_golite062009
monosaccharide binding 3.98668897235502 bayes_pls_golite062009
sialic acid binding 3.52479560815084 bayes_pls_golite062009
carbohydrate binding 2.85222848359059 bayes_pls_golite062009
glycosaminoglycan binding 2.54910720573677 bayes_pls_golite062009
polysaccharide binding 2.35704408824093 bayes_pls_golite062009
pattern binding 2.08318151477871 bayes_pls_golite062009
growth factor activity 2.0453811346021 bayes_pls_golite062009
binding 2.03451078500546 bayes_pls_golite062009
receptor binding 2.00166772827156 bayes_pls_golite062009
hyaluronic acid binding 1.98794610872387 bayes_pls_golite062009
protein binding 1.92861594281923 bayes_pls_golite062009
oligosaccharide binding 1.5609945262091 bayes_pls_golite062009
heparin binding 1.12629317075629 bayes_pls_golite062009
extracellular matrix structural constituent 1.01437131878977 bayes_pls_golite062009
mannose binding 0.861105897314574 bayes_pls_golite062009
integrin binding 0.717993719687201 bayes_pls_golite062009
galactose binding 0.6371384727372 bayes_pls_golite062009
receptor activity 0.427193670352265 bayes_pls_golite062009
cell surface binding 0.421177554796027 bayes_pls_golite062009
fucose binding 0.2864673180945 bayes_pls_golite062009
transmembrane receptor activity 0.0794028045607619 bayes_pls_golite062009

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