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View Structure Prediction Details

Protein: gi|1279761, gi|7...
Organism: Homo sapiens
Length: 341 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1279761, gi|7....

Description E-value Query
Range
Subject
Range
gi|109075948 - gi|109075948|ref|XP_001086103.1| PREDICTED: similar to ADP-ribosylation factor interacting protein 1...
0.0 [1..341] [142..477]
gi|73977955 - gi|73977955|ref|XP_867776.1| PREDICTED: similar to ADP-ribosylation factor interacting protein 1 iso...
0.0 [1..341] [1..341]
gi|219841958, gi... - gi|82890050|ref|XP_904285.1| PREDICTED: ADP-ribosylation factor interacting protein 1 isoform 4 [Mus...
0.0 [1..341] [1..341]
ENSPTRT00000030708 - null
ARFIP1 - ADP-ribosylation factor interacting protein 1
0.0 [1..341] [1..373]
ARFP1_RAT - Arfaptin-1 OS=Rattus norvegicus GN=Arfip1 PE=1 SV=1
0.0 [1..341] [1..366]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQESPKNSA AEIPVTSNGE VDDSREHSFN RDLKHSLPSG LGLSETQITS HGFDNTKEGV  60
   61 IEAGAFQGGQ RTQTKSGPVI LADEIKNPAM EKLELVRKWS LNT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.206 N/A N/A d.52.3 Prokaryotic type KH domain (KH-domain type II)

Predicted Domain #2
Region A:
Residues: [104-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKCTRQIISE KLGRGSRTVD LELEAQIDIL RDNKKKYENI LKLAQTLSTQ LFQMVHTQRQ  60
   61 LGDAFADLSL KSLELHEEFG YNADTQKLLA KNGETLLGAI NFFIASVNTL VNKTIEDTLM 120
  121 TVKQYESARI EYDAYRTDLE ELNLGPRDAN TLPKIEQSQH LFQAHKEKYD KMRNDVSVKL 180
  181 KFLEENKVKV LHNQLVLFHN AIAAYFAGNQ KQLEQTLKQF HIKLKTPGVD APSWLEEQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.0
Match: 1i49A
Description: Arfaptin, Rac-binding fragment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.124619761789 bayes_pls_golite062009
binding 2.43584893484993 bayes_pls_golite062009
protein binding 1.87308005875135 bayes_pls_golite062009
signal transducer activity 1.15315260510573 bayes_pls_golite062009
molecular transducer activity 1.15315260510573 bayes_pls_golite062009
GTPase binding 0.50066793947946 bayes_pls_golite062009
GTPase regulator activity 0.459881864914566 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.456472132383968 bayes_pls_golite062009
enzyme regulator activity 0.180886944097381 bayes_pls_golite062009
small GTPase binding 0.0531578648468707 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle