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View Structure Prediction Details

Protein: SLC26A5
Organism: Homo sapiens
Length: 744 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLC26A5.

Description E-value Query
Range
Subject
Range
gi|31096302 - gi|31096302|gb|AAP43685.1| prestin [Homo sapiens]
0.0 [1..744] [1..746]
S26A5_MOUSE - Prestin OS=Mus musculus GN=Slc26a5 PE=2 SV=3
0.0 [1..744] [1..744]
gi|73981812 - gi|73981812|ref|XP_540393.2| PREDICTED: similar to Prestin (Solute carrier family 26, member 5) isof...
0.0 [1..744] [1..744]
S26A5_MERUN - Prestin OS=Meriones unguiculatus GN=SLC26A5 PE=1 SV=1
0.0 [1..744] [1..744]
S26A5_RAT - Prestin OS=Rattus norvegicus GN=Slc26a5 PE=1 SV=1
0.0 [1..744] [1..744]
gi|76615180 - gi|76615180|ref|XP_616468.2| PREDICTED: similar to SLC26A5 protein isoform 1 [Bos taurus]
0.0 [1..739] [1..739]

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Predicted Domain #1
Region A:
Residues: [1-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDHAEENEIL AATQRYYVER PIFSHPVLQE RLHTKDKVPD SIADKLKQAF TCTPKKIRNI  60
   61 IYMFLPITKW LPAYKFKEYV LGDLVSGIST GVLQLPQGLA FAMLAAVPPI FGLYSSFYPV 120
  121 IMYCFLGTSR HISIGPFAVI SLMIGGVAVR LVPDDIVIPG GVNATNGTEA RDALRVKVAM 180
  181 SVTLLSGIIQ FCLGVCRFGF VAIYLTEPLV RGFTTAAAVH VFTSMLKYLF GVKTKRYSGI 240
  241 FSVVYSTVAV LQNVKN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [257-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNVCSLGVGL MVFGLLLGGK EFNERFKEKL PAPIPLEFFA VVMGTGISAG FNLKESYNVD  60
   61 VVGTLPLGLL PPANPDTSLF HLVYVDAIAI AIVGFSVTIS MAKTLANKHG YQVDGNQELI 120
  121 ALGLCNSIGS LFQTFSISCS LSRSLVQEGT GGKTQLAGCL ASLMILLVIL ATGFLFESLP 180
  181 QAVLSAIVIV NLKGMFMQFS DLPFFWRTSK IELTIWLTTF VSSLFLGLDY GLITAVIIAL 240
  241 LTVIYRTQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [505-601]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSYKVLGKL PETDVYIDID AYEEVKEIPG IKIFQINAPI YYANSDLYSN ALKRKTGVNP  60
   61 AVIMGARRKA MRKYAKEVGN ANMANATVVK ADAEVDG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.2
Match: 1tidB
Description: Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: Poised for phosphorylation complex with ATP, crystal form I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.14643407404573 bayes_pls_golite062009
protein binding 1.48694301635456 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [602-744]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDATKPEEED GEVKYPPIVI KSTFPEEMQR FMPPGDNVHT VILDFTQVNF IDSVGVKTLA  60
   61 GIVKEYGDVG IYVYLAGCSA QVVNDLTRNR FFENPALWEL LFHSIHDAVL GSQLREALAE 120
  121 QEASAPPSQE DLEPNATPAT PEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 1tidB
Description: Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: Poised for phosphorylation complex with ATP, crystal form I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.23164933258149 bayes_pls_golite062009
protein binding 1.6097880273634 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle