| Protein: | SRGAP3 |
| Organism: | Homo sapiens |
| Length: | 1099 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRGAP3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1099] | [1..1099] |
|
|
0.0 | [1..1099] | [1..1099] |
|
|
0.0 | [1..1099] | [1..1099] |
|
|
0.0 | [1..1099] | [1..1099] |
|
|
0.0 | [1..1099] | [1..1099] |
|
|
0.0 | [1..1099] | [1..1075] |
|
Region A: Residues: [1-324] |
1 11 21 31 41 51
| | | | | |
1 MSSQTKFKKD KEIIAEYEAQ IKEIRTQLVE QFKCLEQQSE SRLQLLQDLQ EFFRRKAEIE 60
61 LEYSRSLEKL AERFSSKIRS SREHQFKKDQ YLLSPVNCWY LVLHQTRRES RDHATLNDIF 120
121 MNNVIVRLSQ ISEDVIRLFK KSKEIGLQMH EELLKVTNEL YTVMKTYHMY HAESISAESK 180
181 LKEAEKQEEK QFNKSGDLSM NLLRHEDRPQ RRSSVKKIEK MKEKRQAKYS ENKLKCTKAR 240
241 NDYLLNLAAT NAAISKYYIH DVSDLIDCCD LGFHASLART FRTYLSAEYN LETSRHEGLD 300
301 VIENAVDNLD SRSDKHTVMD MCNQ
|
| Detection Method: |  |
| Confidence: | 23.0 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [325-698] |
1 11 21 31 41 51
| | | | | |
1 VFCPPLKFEF QPHMGDEVCQ VSAQQPVQTE LLMRYHQLQS RLATLKIENE EVRKTLDATM 60
61 QTLQDMLTVE DFDVSDAFQH SRSTESVKSA ASETYMSKIN IAKRRANQQE TEMFYFTKFK 120
121 EYVNGSNLIT KLQAKHDLLK QTLGEGERAE CGTTRPPCLP PKPQKMRRPR PLSVYSHKLF 180
181 NGSMEAFIKD SGQAIPLVVE SCIRYINLYG LQQQGIFRVP GSQVEVNDIK NSFERGEDPL 240
241 VDDQNERDIN SVAGVLKLYF RGLENPLFPK ERFQDLISTI KLENPAERVH QIQQILVTLP 300
301 RVVIVVMRYL FAFLNHLSQY SDENMMDPYN LAICFGPTLM HIPDGQDPVS CQAHINEVIK 360
361 TIIIHHEAIF PSPR
|
| Detection Method: | |
| Confidence: | 47.0 |
| Match: | 1xa6A |
| Description: | Crystal Structure of the Human Beta2-Chimaerin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| Rho GTPase activator activity | 4.58620967349979 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 4.48279904625182 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.42802398019084 | bayes_pls_golite062009 |
| binding | 2.79128751898373 | bayes_pls_golite062009 |
| GTPase regulator activity | 2.70614727793157 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 2.68579854252375 | bayes_pls_golite062009 |
| actin binding | 2.59114492135519 | bayes_pls_golite062009 |
| tubulin binding | 2.31518443151057 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 2.06038764955701 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.9750017471254 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.95738547986197 | bayes_pls_golite062009 |
| motor activity | 1.59872328451279 | bayes_pls_golite062009 |
| microtubule binding | 1.39416664093439 | bayes_pls_golite062009 |
| Rho GTPase binding | 1.34980300847466 | bayes_pls_golite062009 |
| protein binding | 1.29100556128076 | bayes_pls_golite062009 |
| molecular transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| signal transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 1.09070479183477 | bayes_pls_golite062009 |
| transcription regulator activity | 1.08577758274384 | bayes_pls_golite062009 |
| Rho guanyl-nucleotide exchange factor activity | 0.967362611034944 | bayes_pls_golite062009 |
| Ras guanyl-nucleotide exchange factor activity | 0.958295643211986 | bayes_pls_golite062009 |
| actin filament binding | 0.937704425867942 | bayes_pls_golite062009 |
| GTPase activator activity | 0.717730683557543 | bayes_pls_golite062009 |
| nucleic acid binding | 0.480348726111787 | bayes_pls_golite062009 |
| receptor activity | 0.434186339265983 | bayes_pls_golite062009 |
| DNA binding | 0.418154636457321 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.38335246506929 | bayes_pls_golite062009 |
| enzyme activator activity | 0.298334474872045 | bayes_pls_golite062009 |
| microfilament motor activity | 0.0746966011130201 | bayes_pls_golite062009 |
|
Region A: Residues: [699-876] |
1 11 21 31 41 51
| | | | | |
1 ELEGPVYEKC MAGGEEYCDS PHSEPGAIDE VDHDNGTEPH TSDEEVEQIE AIAKFDYMGR 60
61 SPRELSFKKG ASLLLYHRAS EDWWEGRHNG VDGLIPHQYI VVQDMDDAFS DSLSQKADSE 120
121 ASSGPLLDDK ASSKNDLQSP TEHISDYGFG GVMGRVRLRS DGAAIPRRRS GGDTHSPP
|
| Detection Method: | |
| Confidence: | 7.045757 |
| Match: | 2dl8A |
| Description: | No description for 2dl8A was found. |
|
Region A: Residues: [877-928] |
1 11 21 31 41 51
| | | | | |
1 RGLGPSIDTP PRAAACPSSP HKIPLTRGRI ESPEKRRMAT FGSAGSINYP DK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [929-1099] |
1 11 21 31 41 51
| | | | | |
1 KALSEGHSMR STCGSTRHSS LGDHKSLEAE ALAEDIEKTM STALHELREL ERQNTVKQAP 60
61 DVVLDTLEPL KNPPGPVSSE PASPLHTIVI RDPDAAMRRS SSSSTEMMTT FKPALSARLA 120
121 GAQLRPPPMR PVRPVVQHRS SSSSSSGVGS PAVTPTEKMF PNSSADKSGT M
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
