YRC Public Data Repository - Protein Structure Prediction

Protein:	CPSF3
Organism:	Homo sapiens
Length:	684 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CPSF3.

Description	E-value	Query Range	Subject Range
gi\|194220982 - gi\|194220982\|ref\|XP_001502516.2\| PREDICTED: similar to Cleavage and Polyadenylation Specifity Factor... gi\|73979708 - gi\|73979708\|ref\|XP_540075.2\| PREDICTED: similar to Cleavage and polyadenylation specificity factor, ...	0.0	[1..684]	[1..684]
CPSF3_BOVIN - Cleavage and polyadenylation specificity factor subunit 3 OS=Bos taurus GN=CPSF3 PE=1 SV=1	0.0	[1..684]	[1..684]
gi\|114576010, gi... - gi\|114576010\|ref\|XP_001154730.1\| PREDICTED: hypothetical protein isoform 8 [Pan troglodytes], gi\|114...	0.0	[1..684]	[1..684]
CPSF3_MOUSE - Cleavage and polyadenylation specificity factor subunit 3 OS=Mus musculus GN=Cpsf3 PE=1 SV=2	0.0	[1..684]	[1..684]
gi\|15079675 - gi\|15079675\|gb\|AAH11654.1\| Cleavage and polyadenylation specific factor 3, 73kDa [Homo sapiens] gi\|157929136 - gi\|157929136\|gb\|ABW03853.1\| cleavage and polyadenylation specific factor 3, 73kDa [synthetic constru...	0.0	[1..684]	[1..684]
gi\|67969340 - gi\|67969340\|dbj\|BAE01022.1\| unnamed protein product [Macaca fascicularis]	0.0	[1..684]	[1..684]

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Predicted Domain #1

Region A:
Residues: [1-470]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAIPAEESD QLLIRPLGAG QEVGRSCIIL EFKGRKIMLD CGIHPGLEGM DALPYIDLID  60
   61 PAEIDLLLIS HFHLDHCGAL PWFLQKTSFK GRTFMTHATK AIYRWLLSDY VKVSNISADD 120
  121 MLYTETDLEE SMDKIETINF HEVKEVAGIK FWCYHAGHVL GAAMFMIEIA GVKLLYTGDF 180
  181 SRQEDRHLMA AEIPNIKPDI LIIESTYGTH IHEKREEREA RFCNTVHDIV NRGGRGLIPV 240
  241 FALGRAQELL LILDEYWQNH PELHDIPIYY ASSLAKKCMA VYQTYVNAMN DKIRKQININ 300
  301 NPFVFKHISN LKSMDHFDDI GPSVVMASPG MMQSGLSREL FESWCTDKRN GVIIAGYCVE 360
  361 GTLAKHIMSE PEEITTMSGQ KLPLKMSVDY ISFSAHTDYQ QTSEFIRALK PPHVILVHGE 420
  421 QNEMARLKAA LIREYEDNDE VHIEVHNPRN TEAVTLNFRG EKLAKVMGFL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	103.0
Match:	2i7tA
Description:	No description for 2i7tA was found.

Predicted Domain #2

Region A:
Residues: [471-684]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADKKPEQGQR VSGILVKRNF NYHILSPCDL SNYTDLAMST VKQTQAIPYT GPFNLLCYQL  60
   61 QKLTGDVEEL EIQEKPALKV FKNITVIQEP GMVVLEWLAN PSNDMYADTV TTVILEVQSN 120
  121 PKIRKGAVQK VSKKLEMHVY SKRLEIMLQD IFGEDCVSVK DDSILSVTVD GKTANLNLET 180
  181 RTVECEEGSE DDESLREMVE LAAQRLYEAL TPVH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits