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View Structure Prediction Details

Protein: LACE1
Organism: Homo sapiens
Length: 481 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LACE1.

Description E-value Query
Range
Subject
Range
LACE1_RAT - Lactation elevated protein 1 OS=Rattus norvegicus GN=Lace1 PE=2 SV=1
0.0 [1..481] [1..480]
gi|21668096, gi|... - gi|21919411|ref|NP_665686.1| lactation elevated 1 [Mus musculus], gi|21668096|gb|AAM74227.1|AF520417...
0.0 [1..481] [1..480]
gi|109073117 - gi|109073117|ref|XP_001093944.1| PREDICTED: similar to lactation elevated 1 [Macaca mulatta]
0.0 [1..481] [1..481]
gi|73973975 - gi|73973975|ref|XP_539073.2| PREDICTED: similar to lactation elevated 1 [Canis familiaris]
0.0 [44..481] [19..457]
gi|50744610 - gi|50744610|ref|XP_419799.1| PREDICTED: similar to lactation elevated 1; CG8520 gene product; lactat...
0.0 [63..481] [253..684]
gi|58391938, gi|... - gi|58391938|ref|XP_318985.2| ENSANGP00000014807 [Anopheles gambiae str. PEST], gi|55236088|gb|EAA144...
0.0 [58..480] [2..436]
gi|66517496 - gi|66517496|ref|XP_624398.1| PREDICTED: similar to lactation elevated 1 [Apis mellifera]
3.0E-92 [72..476] [26..432]

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Predicted Domain #1
Region A:
Residues: [1-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASWSLLVT LRPLAQSPLR GRCVGCGAWA AALAPLATAP GKPFWKAYTV QTSESMTPTA  60
   61 TSETYLKALA VCHGPLDHYD FLIKAHELKD DEHQRRVIQC LQKLHEDLKG YNIEAEGLFS 120
  121 KLFSRSKPPR GLYVYGDVGT GKTMVMDMFY AYVEMKRKKR VHFHGFMLDV HKRIHRLKQS 180
  181 LPKRKPGFMA KSYDPIAPIA EEISEEACLL CFDEFQVTDI ADAMILKQLF ENLFKNGVVV 240
  241 VATSNRPPED LYKNGLQRAN FVPFIAVLKE YCNTVQLDSG IDYRKRELPA AGKLYYLTSE 300
  301 ADVEAVMDKL FDELAQKQND LTRPRILKVQ GRELRLNKAC GTVADCTFEE LCERPLGASD 360
  361 YLELSKNFDT IFLRNIPQF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.69897
Match: 1oz4A
Description: VCP/p97
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [380-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLANRTQGRR FITLIDNFYD LKVRIICSAS TPISSLFLHQ HHDSELEQSR ILMDDLGLSQ  60
   61 DSAEGLSMFT GEEEIFAFQR TISRLTEMQT EQYWNEGDRT KK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle