| Protein: | gi|55957392, gi|... |
| Organism: | Homo sapiens |
| Length: | 1204 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|55957392, gi|....
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [339..1201] | [2042..2900] |
|
|
0.0 | [339..1201] | [989..1876] |
|
|
5.0E-94 | [339..1201] | [1042..1929] |
|
|
6.0E-94 | [339..1201] | [1041..1928] |
|
|
6.0E-94 | [339..1201] | [1045..1932] |
|
Region A: Residues: [1-320] |
1 11 21 31 41 51
| | | | | |
1 MSFFNFRKIF KLGSEKKKKQ YEHVKRDLNP EDFWEIIGEL GDGAFGKVYK AQNKETSVLA 60
61 AAKVIDTKSE EELEDYMVEI DILASCDHPN IVKLLDAFYY ENNLWILIEF CAGGAVDAVM 120
121 LELERPLTES QIQVVCKQTL DALNYLHDNK IIHRDLKAGN ILFTLDGDIK LADFGVSAKN 180
181 TRTIQRRDSF IGTPYWMAPE VVMCETSKDR PYDYKADVWS LGITLIEMAE IEPPHHELNP 240
241 MRVLLKIAKS EPPTLAQPSR WSSNFKDFLK KCLEKNVDAR WTTSQLLQHP FVTVDSNKPI 300
301 RELIAEAKAE VTEEVEDGKE
|
| Detection Method: |  |
| Confidence: | 60.09691 |
| Match: | 2j51A |
| Description: | No description for 2j51A was found. |
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 4.62392503670521 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 2.79505438761262 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 1.93176092222748 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 1.90354666768303 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.71452519680794 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.27184436658773 | bayes_pls_golite062009 |
| insulin receptor activity | 1.22442673174261 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| nucleic acid binding | 1.16049201286103 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| PTB domain binding | 0.9900774724568 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 0.872782211382796 | bayes_pls_golite062009 |
| insulin binding | 0.614254468447749 | bayes_pls_golite062009 |
| transporter activity | 0.595111702412257 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.41384976209545 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| telethonin binding | 0.386946764759301 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| protein complex binding | 0.343240719858581 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.32649770094749 | bayes_pls_golite062009 |
| signal transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| molecular transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| MAP kinase activity | 0.26024936404169 | bayes_pls_golite062009 |
| cation channel activity | 0.245400615103891 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.214293154365587 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.0922946791401962 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [321-407] |
1 11 21 31 41 51
| | | | | |
1 EDEEEETENS LPIPASKRAS SDLSIASSEE DKLSQNACIL ESVSEKTERS NSEDKLNSKI 60
61 LNEKPTTDEP EKAVEDINEH ITDAQLE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [408-525] |
1 11 21 31 41 51
| | | | | |
1 AMTELHDRTA VIKENEREKR PKLENLPDTE DQETVDINSV SEGKENNIMI TLETNIEHNL 60
61 KSEEEKDQEK QQMFENKLIK SEEIKDTILQ TVDLVSQETG EKEANIQAVD SEVGLTKE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [526-600] |
1 11 21 31 41 51
| | | | | |
1 DTQEKLGEDD KTQKDVISNT SDVIGTCEAA DVAQKVDEDS AEDTQSNDGK EVVEVGQKLI 60
61 NKPMVGPEAG GTKEV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [601-934] |
1 11 21 31 41 51
| | | | | |
1 PIKEIVEMNE IEEGKNKEQA INSSENIMDI NEEPGTTEGE EITESSSTEE MEVRSVVADT 60
61 DQKALGSEVQ DASKVTTQID KEKKEIPVSI KKEPEVTVVS QPTEPQPVLI PSININSDSG 120
121 ENKEEIGSLS KTETILPPES ENPKENDNDS GTGSTADTSS IDLNLSISSF LSKTKDSGSI 180
181 SLQETRRQKK TLKKTRKFIV DGVEVSVTTS KIVTDSDSKT EELRFLRRQE LRELRFLQKE 240
241 EQRAQQQLNS KLQQQREQIF RRFEQEMMSK KRQYDQEIEN LEKQQKQTIE RLEQEHTNRL 300
301 RDEAKRIKGE QEKELSKFQN MLKNRKKEEQ EFVQ
|
| Detection Method: | |
| Confidence: | 15.0 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [935-1001] |
1 11 21 31 41 51
| | | | | |
1 KQQQELDGSL KKIIQQQKAE LANIERECLN NKQQLMRARE AAIWELEERH LQEKHQLLKQ 60
61 QLKDQYF
|
| Detection Method: | |
| Confidence: | 6.045757 |
| Match: | 1c1gA |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1002-1204] |
1 11 21 31 41 51
| | | | | |
1 MQRHQLLKRH EKETEQMQRY NQRLIEELKN RQTQERARLP KIQRSEAKTR MAMFKKSLRI 60
61 NSTATPDQDR DKIKQFAAQE EKRQKNERMA QHQKHENQMR DLQLQCEANV RELHQLQNEK 120
121 CHLLVEHETQ KLKELDEEHS QELKEWREKL RPRKKTLEEE FARKLQEQEV FFKMTGESEC 180
181 LNPSTQSRIS KFYPIPSLHS TGS
|
| Detection Method: | |
| Confidence: | 4.69897 |
| Match: | 2dfsA |
| Description: | No description for 2dfsA was found. |
