YRC Public Data Repository - Protein Structure Prediction

Protein:	ORC2L
Organism:	Homo sapiens
Length:	577 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORC2L.

Description	E-value	Query Range	Subject Range
gi\|114582759 - gi\|114582759\|ref\|XP_516023.2\| PREDICTED: origin recognition complex, subunit 2 [Pan troglodytes]	0.0	[33..577]	[102..646]
gi\|1142706, gi\|1... - gi\|1587281\|prf\|\|2206380B origin recognition complex subunit, gi\|1142706\|gb\|AAB33970.1\| hORC2L [Homo ...	0.0	[1..577]	[1..577]
gi\|67969346 - gi\|67969346\|dbj\|BAE01025.1\| unnamed protein product [Macaca fascicularis]	0.0	[1..577]	[1..577]
ORC2_RAT - Origin recognition complex subunit 2 OS=Rattus norvegicus GN=Orc2 PE=2 SV=1	0.0	[1..570]	[1..568]
gi\|57110929 - gi\|57110929\|ref\|XP_536028.1\| PREDICTED: similar to origin recognition complex, subunit 2 [Canis fami...	0.0	[1..577]	[2..577]
ORC2_MOUSE - Origin recognition complex subunit 2 OS=Mus musculus GN=Orc2 PE=1 SV=1	0.0	[1..577]	[1..576]
gi\|7650495 - gi\|7650495\|gb\|AAF66068.1\|AF254573_1 origin recognition complex subunit 2 [Cricetulus griseus]	0.0	[1..577]	[1..576]
gi\|148238191, gi... - gi\|54038187\|gb\|AAH84353.1\| Orc2-a protein [Xenopus laevis], gi\|148238191\|ref\|NP_001081070.1\| origin ...	0.0	[1..576]	[1..557]

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Predicted Domain #1

Region A:
Residues: [1-204]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKPELKEDK MLEVHFVGDD DVLNHILDRE GGAKLKKERA QLLVNPKKII KKPEYDLEED  60
   61 DQEVLKDQNY VEIMGRDVQE SLKNGSATGG GNKVYSFQNR KHSEKMAKLA SELAKTPQKS 120
  121 VSFSLKNDPE ITINVPQSSK GHSASDKVQP KNNDKSEFLS TAPRSLRKRL IVPRSHSDSE 180
  181 SEYSASNSED DEGVAQEHEE DTNA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [205-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VIFSQKIQAQ NRVVSAPVGK ETPSKRMKRD KTSDLVEEYF EAHSSSKVLT SDRTLQKLKR  60
   61 AKLDQQTLRN LLSKVSPSFS AELKQLNQQY EK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [297-577]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFHKWMLQLH LGFNIVLYGL GSKRDLLERF RTTMLQDSIH VVINGFFPGI SVKSVLNSIT  60
   61 EEVLDHMGTF RSILDQLDWI VNKFKEDSSL ELFLLIHNLD SQMLRGEKSQ QIIGQLSSLH 120
  121 NIYLIASIDH LNAPLMWDHA KQSLFNWLWY ETTTYSPYTE ETSYENSLLV KQSGSLPLSS 180
  181 LTHVLRSLTP NARGIFRLLI KYQLDNQDNP SYIGLSFQDF YQQCREAFLV NSDLTLRAQL 240
  241 TEFRDHKLIR TKKGTDGVEY LLIPVDNGTL TDFLEKEEEE A

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.975
Match:	2qbyA
Description:	No description for 2qbyA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits