YRC Public Data Repository - Protein Structure Prediction

Protein:	PIN1
Organism:	Homo sapiens
Length:	163 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIN1.

Description	E-value	Query Range	Subject Range
gi\|119604464 - gi\|119604464\|gb\|EAW84058.1\| protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1, isoform... gi\|114675259 - gi\|114675259\|ref\|XP_001161914.1\| PREDICTED: similar to Chain B, Structural Basis For The Phosphoseri...	3.0E-38	[1..163]	[1..163]
gi\|10120798 - gi\|10120798\|pdb\|1F8A\|B Chain B, Structural Basis For The Phosphoserine-Proline Recognition By Group ...	8.0E-38	[1..163]	[5..167]
gi\|61358821 - gi\|61358821\|gb\|AAX41625.1\| protein NIMA-interacting 1 [synthetic construct]	1.0E-37	[1..163]	[1..163]
PIN1_BOVIN - Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Bos taurus GN=PIN1 PE=2 SV=1	2.0E-37	[1..163]	[1..163]
PIN1_MACFA - Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Macaca fascicularis GN=PIN1 PE=2 SV=1	7.0E-37	[1..163]	[1..163]
gi\|41152183, gi\|... - gi\|41152183\|ref\|NP_957042.1\| protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 [Danio...	9.0E-37	[1..162]	[1..158]
gi\|57101996 - gi\|57101996\|ref\|XP_542080.1\| PREDICTED: similar to Peptidyl-prolyl cis-trans isomerase NIMA-interact...	1.0E-36	[1..163]	[1..163]
gi\|66563115 - gi\|66563115\|ref\|XP_624205.1\| PREDICTED: similar to Protein dodo [Apis mellifera]	6.0E-36	[1..162]	[1..161]
gi\|47218949 - gi\|47218949\|emb\|CAF98147.1\| unnamed protein product [Tetraodon nigroviridis]	6.0E-36	[1..162]	[1..155]

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Predicted Domain #1

Region A:
Residues: [1-163]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEEKLPPG WEKRMSRSSG RVYYFNHITN ASQWERPSGN SSSGGKNGQG EPARVRCSHL  60
   61 LVKHSQSRRP SSWRQEKITR TKEEALELIN GYIQKIKSGE EDFESLASQF SDCSSAKARG 120
  121 DLGAFSRGQM QKPFEDASFA LRTGEMSGPV FTDSGIHIIL RTE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.154902
Match:	1f8aB
Description:	Mitotic rotamase PIN1; Mitotic rotamase PIN1, domain 2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits