YRC Public Data Repository - Protein Structure Prediction

Protein:	DDX4
Organism:	Homo sapiens
Length:	724 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DDX4.

Description	E-value	Query Range	Subject Range
gi\|9438227 - gi\|9438227\|gb\|AAF86585.1\| DEAD box RNA helicase [Homo sapiens]	0.0	[1..724]	[1..724]
gi\|109077270 - gi\|109077270\|ref\|XP_001100045.1\| PREDICTED: similar to DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isof...	0.0	[1..724]	[1..725]
DDX4_MACFA - Probable ATP-dependent RNA helicase DDX4 OS=Macaca fascicularis GN=DDX4 PE=2 SV=1	0.0	[1..724]	[1..725]
DDX4_PIG - Probable ATP-dependent RNA helicase DDX4 OS=Sus scrofa GN=DDX4 PE=2 SV=1	0.0	[1..724]	[1..722]
gi\|73949725 - gi\|73949725\|ref\|XP_544339.2\| PREDICTED: similar to DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 [Canis f...	0.0	[1..724]	[1..725]
DDX4_BOVIN - Probable ATP-dependent RNA helicase DDX4 OS=Bos taurus GN=DDX4 PE=2 SV=1	0.0	[1..724]	[1..729]
gi\|114600320 - gi\|114600320\|ref\|XP_517757.2\| PREDICTED: similar to VASA protein [Pan troglodytes]	0.0	[1..724]	[1..703]
gi\|109466049 - gi\|109466049\|ref\|XP_001074861.1\| PREDICTED: similar to Probable ATP-dependent RNA helicase DDX4 (DEA...	0.0	[1..724]	[1..727]

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Predicted Domain #1

Region A:
Residues: [1-204]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDEDWEAEI NPHMSSYVPI FEKDRYSGEN GDNFNRTPAS SSEMDDGPSR RDHFMKSGFA  60
   61 SGRNFGNRDA GECNKRDNTS TMGGFGVGKS FGNRGFSNSR FEDGDSSGFW RESSNDCEDN 120
  121 PTRNRGFSKR GGYRDGNNSE ASGPYRRGGR GSFRGCRGGF GLGSPNNDLD PDECMQRTGG 180
  181 LFGSRRPVLS GTGNGDTSQS RSGS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.69897
Match:	1y0fA
Description:	No description for 1y0fA was found.

Predicted Domain #2

Region A:
Residues: [205-664]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSERGGYKGL NEEVITGSGK NSWKSEAEGG ESSDTQGPKV TYIPPPPPED EDSIFAHYQT  60
   61 GINFDKYDTI LVEVSGHDAP PAILTFEEAN LCQTLNNNIA KAGYTKLTPV QKYSIPIILA 120
  121 GRDLMACAQT GSGKTAAFLL PILAHMMHDG ITASRFKELQ EPECIIVAPT RELVNQIYLE 180
  181 ARKFSFGTCV RAVVIYGGTQ LGHSIRQIVQ GCNILCATPG RLMDIIGKEK IGLKQIKYLV 240
  241 LDEADRMLDM GFGPEMKKLI SCPGMPSKEQ RQTLMFSATF PEEIQRLAAE FLKSNYLFVA 300
  301 VGQVGGACRD VQQTVLQVGQ FSKREKLVEI LRNIGDERTM VFVETKKKAD FIATFLCQEK 360
  361 ISTTSIHGDR EQREREQALG DFRFGKCPVL VATSVAARGL DIENVQHVIN FDLPSTIDEY 420
  421 VHRIGRTGRC GNTGRAISFF DLESDNHLAQ PLVKVLTDAQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	78.221849
Match:	2db3A
Description:	No description for 2db3A was found.

Predicted Domain #3

Region A:
Residues: [665-724]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDVPAWLEEI AFSTYIPGFS GSTRGNVFAS VDTRKGKSTL NTAGFSSSQA PNPVDDESWD  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.39794
Match:	2ibmA
Description:	No description for 2ibmA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits