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View Structure Prediction Details

Protein: RBP1
Organism: Homo sapiens
Length: 135 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBP1.

Description E-value Query
Range
Subject
Range
gi|114589486 - gi|114589486|ref|XP_001158395.1| PREDICTED: similar to Retinol-binding protein I, cellular (Cellular...
2.0E-50 [1..135] [63..197]
RET1_MOUSE - Retinol-binding protein 1 OS=Mus musculus GN=Rbp1 PE=1 SV=2
1.0E-44 [1..134] [1..134]
RET1_RAT - Retinol-binding protein 1 OS=Rattus norvegicus GN=Rbp1 PE=1 SV=2
2.0E-44 [1..134] [1..134]
CCDS3110.1_1 - null
gi|109049080 - gi|109049080|ref|XP_001113466.1| PREDICTED: retinol binding protein 1, cellular [Macaca mulatta]
2.0E-44 [1..135] [1..135]
gi|60829986 - gi|60829986|gb|AAX36905.1| retinol binding protein 1 [synthetic construct]
1.0E-43 [1..135] [1..135]
gi|809309, gi|15... - gi|809309|pdb|1CRB| Chain , Cellular Retinol Binding Protein (Crbp) Complexed With All-Trans Retin...
RET1_RAT - (P02696) Retinol-binding protein I, cellular (Cellular retinol-binding protein) (CRBP)
1.0E-43 [2..134] [1..133]
RET1_BOVIN - Retinol-binding protein 1 OS=Bos taurus GN=RBP1 PE=1 SV=4
5.0E-43 [1..134] [1..134]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVDFTGYWK MLVNENFEEY LRALDVNVAL RKIANLLKPD KEIVQDGDHM IIRTLSTFRN  60
   61 YIMDFQVGKE FEEDLTGIDD RKCMTTVSWD GDKLQCVQKG EKEGRGWTQW IEGDELHLEM 120
  121 RVEGVVCKQV FKKVQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 1jbhA
Description: Cellular retinol-binding protein II (CRBP)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
long-chain fatty acid transporter activity 5.31242454679135 bayes_pls_golite062009
fatty acid transporter activity 5.05947161650978 bayes_pls_golite062009
lipid transporter activity 4.30505384117861 bayes_pls_golite062009
retinoid binding 3.86745158299736 bayes_pls_golite062009
isoprenoid binding 3.80802424204178 bayes_pls_golite062009
lysophospholipid transporter activity 3.53484598441971 bayes_pls_golite062009
retinol binding 3.41359399354212 bayes_pls_golite062009
binding 2.93830472620404 bayes_pls_golite062009
transcription regulator activity 2.27413749831465 bayes_pls_golite062009
transporter activity 2.15627660314839 bayes_pls_golite062009
transcription repressor activity 1.45696778890481 bayes_pls_golite062009
protein binding 1.23450129884619 bayes_pls_golite062009
prostaglandin-D synthase activity 1.18764036773412 bayes_pls_golite062009
lipid binding 1.0002255159651 bayes_pls_golite062009
retinol transporter activity 0.811095267558536 bayes_pls_golite062009
fatty acid binding 0.761923641769607 bayes_pls_golite062009
substrate-specific transporter activity 0.670647472301401 bayes_pls_golite062009
retinoic acid binding 0.539496110498594 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.50851501669551 bayes_pls_golite062009
bile acid binding 0.37501307074598 bayes_pls_golite062009

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