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View Structure Prediction Details

Protein: PHPT1
Organism: Homo sapiens
Length: 125 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHPT1.

Description E-value Query
Range		 Subject
Range
gi|114794585 - gi|114794585|pdb|2HW4|A Chain A, Crystal Structure Of Human Phosphohistidine Phosphatase
 2.0E-48 [5..125] [24..144]
JANA_DROPS - Sex-regulated protein janus-A OS=Drosophila pseudoobscura pseudoobscura GN=janA PE=3 SV=2
JANA_DROPS - Sex-regulated protein janus-A - Drosophila pseudoobscura (Fruit fly)
 4.0E-48 [1..125] [26..149]
PHP14_RABIT - 14 kDa phosphohistidine phosphatase OS=Oryctolagus cuniculus GN=PHPT1 PE=1 SV=1
 8.0E-48 [1..125] [1..125]
JANA_DROER - Sex-regulated protein janus-A OS=Drosophila erecta GN=janA PE=3 SV=1
 2.0E-47 [1..125] [17..135]
PHP14_PONAB - 14 kDa phosphohistidine phosphatase OS=Pongo abelii GN=PHPT1 PE=2 SV=1
PHP14_PONPY - 14 kDa phosphohistidine phosphatase - Pongo pygmaeus (Orangutan)
 2.0E-47 [1..125] [1..125]
JANA_DROSI - Sex-regulated protein janus-A OS=Drosophila simulans GN=janA PE=3 SV=1
 2.0E-47 [1..125] [17..135]
JANA_DROYA - Sex-regulated protein janus-A OS=Drosophila yakuba GN=janA PE=3 SV=1
JANA_DROTE - Sex-regulated protein janus-A OS=Drosophila teissieri GN=janA PE=3 SV=1
 2.0E-47 [1..125] [17..135]
JANA_DROOR - Sex-regulated protein janus-A OS=Drosophila orena GN=janA PE=3 SV=1
 2.0E-47 [1..125] [17..135]

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Predicted Domain #1
Region A:
Residues: [1-125] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVADLALIP DVDIDSDGVF KYVLIRVHSA PRSGAPAAES KEIVRGYKWA EYHADIYDKV  60
   61 SGDMQKQGCD CECLGGGRIS HQSQDKKIHV YGYSMAYGPA QHAISTEKIK AKYPDYEVTW 120
  121 ANDGY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.154902
Match: 2nmmA
Description: No description for 2nmmA was found.

Predicted functions:

Term Confidence Notes
phosphatase activity 2.90928003199671 bayes_pls_golite062009
phosphoric ester hydrolase activity 2.8059832540187 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.3476006253199 bayes_pls_golite062009
hydrolase activity 1.95386660796537 bayes_pls_golite062009
kinase activity 0.860949548091305 bayes_pls_golite062009
binding 0.837330942729674 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.726151562817894 bayes_pls_golite062009
protein binding 0.450003413759302 bayes_pls_golite062009
transferase activity 0.420759440852261 bayes_pls_golite062009
catalytic activity 0.24846317916908 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle