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View Structure Prediction Details

Protein: GLTP
Organism: Homo sapiens
Length: 209 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLTP.

Description E-value Query
Range
Subject
Range
gi|34872669, gi|... - ref|XP_213793.2| similar to Glycolipid transfer protein [Rattus norvegicus], gi|109496081|ref|XP_213...
4.0E-76 [1..209] [140..348]
gi|73995333 - gi|73995333|ref|XP_854394.1| PREDICTED: similar to Glycolipid transfer protein (GLTP) [Canis familia...
1.0E-72 [1..209] [1..209]
gi|75765252 - gi|75765252|pdb|1TFJ|A Chain A, Crystal Structure Of Bovine Glycolipid Transfer Protein In Complex W...
2.0E-72 [2..209] [12..219]
GLTP_MOUSE - Glycolipid transfer protein OS=Mus musculus GN=Gltp PE=1 SV=3
5.0E-72 [1..209] [1..209]
gi|83754990 - gi|83754990|pdb|2EVT|A Chain A, Crystal Structure Of D48v Mutant Of Human Glycolipid Transfer Protei...
1.0E-71 [1..209] [1..209]

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Predicted Domain #1
Region A:
Residues: [1-209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLAEHLLK PLPADKQIET GPFLEAVSHL PPFFDCLGSP VFTPIKADIS GNITKIKAVY  60
   61 DTNPAKFRTL QNILEVEKEM YGAEWPKVGA TLALMWLKRG LRFIQVFLQS ICDGERDENH 120
  121 PNLIRVNATK AYEMALKKYH GWIVQKIFQA ALYAAPYKSD FLKALSKGQN VTEEECLEKI 180
  181 RLFLVNYTAT IDVIYEMYTQ MNAELNYKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.39794
Match: 1swxA
Description: Crystal structure of a human glycolipid transfer protein in apo-form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycolipid binding 5.49972539331808 bayes_pls_golite062009
glycolipid transporter activity 5.12647077378187 bayes_pls_golite062009
lipid transporter activity 4.58296886790648 bayes_pls_golite062009
lipid binding 2.57182773557624 bayes_pls_golite062009
transporter activity 2.55928656852707 bayes_pls_golite062009
substrate-specific transporter activity 2.14215782778459 bayes_pls_golite062009
binding 1.15505977330425 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle