YRC Public Data Repository - Protein Structure Prediction

Protein:	GTF2E2
Organism:	Homo sapiens
Length:	291 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GTF2E2.

Description	E-value	Query Range	Subject Range
gi\|73979353 - gi\|73979353\|ref\|XP_532814.2\| PREDICTED: similar to Transcription initiation factor IIE beta subunit ...	401.0	[0..1]	[291..122]
gi\|109086076 - gi\|109086076\|ref\|XP_001083643.1\| PREDICTED: general transcription factor IIE, polypeptide 2, beta 34...	399.0	[0..1]	[291..1]
gi\|61366471, gi\|... - gi\|61366471\|gb\|AAX42864.1\| general transcription factor IIE polypeptide 2 beta [synthetic construct]...	398.0	[0..1]	[291..1]
T2EB_BOVIN - General transcription factor IIE subunit 2 OS=Bos taurus GN=GTF2E2 PE=2 SV=1	398.0	[0..1]	[291..1]
gi\|228300 - gi\|228300\|prf\|\|1802389A transcription factor IIE:SUBUNIT=beta	397.0	[0..1]	[291..1]
gi\|34878722, gi\|... - gi\|34878722\|ref\|XP_224929.2\| PREDICTED: similar to Transcription initiation factor IIE beta subunit ...	395.0	[0..1]	[291..1]
T2EB_MOUSE - General transcription factor IIE subunit 2 OS=Mus musculus GN=Gtf2e2 PE=1 SV=2	390.0	[0..1]	[291..1]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPSLLRERE LFKKRALSTP VVEKRSASSE SSSSSSKKKK TKVEHGGSSG SKQNSDHSNG  60
   61 SFNLKALSGS SGYKFGVLAK IVNYMKTRHQ RGDTHPLTLD EILDETQHLD IGLKQKQWLM 120
  121 TEALVNNPKI EVIDGKYAFK PKYNVRDKKA LLRLLDQH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.154902
Match:	1d8jA
Description:	The central core domain of TFIIE beta
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [159-291]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQRGLGGILL EDIEEALPNS QKAVKALGDQ ILFVNRPDKK KILFFNDKSC QFSVDEEFQK  60
   61 LWRSVTVDSM DEEKIEEYLK RQGISSMQES GPKKVAPIQR RKKPASQKKR RFKTHNEHLA 120
  121 GVLKDYSDIT SSK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits