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View Structure Prediction Details

Protein: gi|115480359, gi...
Organism: Oryza sativa Japonica Group
Length: 532 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|115480359, gi....

Description E-value Query
Range
Subject
Range
CP2CP_MESAU - Cytochrome P450 2C25 OS=Mesocricetus auratus GN=CYP2C25 PE=2 SV=1
294.0 [0..95] [531..1]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAWVRRQPPK VKAFLAVVTG MAALVFIRFI VHDHDNLFVA AEAAHALGIA VLIYKLTKEK  60
   61 TCAGLSLKSQ DLTALFLAVR LYCSFVMEYD IHTVLDTATL AATLFVIYMI RFK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [114-532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRPTYMVDKD NFALYYVVVP CAVLALLIHP STSHNIVNRI SWAFCVYLEA VSVLPQLRLM  60
   61 QNTKIVEPFT AHYVFALGVA RFLSCAHWVL QVLDTRGRLL TALGYGLWPS MVLLSEIVQT 120
  121 FILADFCYYY VKSLVGGQLV LRLPSGVVQN GERKSYDVLQ RFGFHTICMV AFGHDLPCLA 180
  181 DGGVMEDARS DFMHSFGEAQ NLVVGRFFDL IEVSWKIKKW LNVGTIRRLR KAIADVHTFA 240
  241 MDIVRARRQS ASVQDRDDVL SRFVASDEHS DEVLRDIVLS FLIVGRDTTA SGLSWFFCLL 300
  301 SSRPDVVARI ADEVRAVRKP TDTRLGEPFR FDALWEMHYL HAALTESMRL YPPASVVRGG 360
  361 RHTPRRHARP RRLVRDVQRI RHRARTAWST GRSGGSARTA CSSRRARERE MPASQRKRD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.522879
Match: 1pq2A
Description: Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxygen binding 4.01188516987152 bayes_pls_golite062009
iron ion binding 1.26638814135091 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1.11801727223629 bayes_pls_golite062009
monooxygenase activity 1.10206898259012 bayes_pls_golite062009
binding 1.0881336564542 bayes_pls_golite062009
steroid hydroxylase activity 1.04300167237097 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
electron carrier activity 0.168631835839473 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle