YRC Public Data Repository - Protein Structure Prediction

Protein:	CYB5B
Organism:	Homo sapiens
Length:	146 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYB5B.

Description	E-value	Query Range	Subject Range
gi\|12230015, gi\|... - gi\|2662291\|dbj\|BAA23735.1\| cytochrome b5 [Homo sapiens], sp\|O43169\|CYM5_HUMAN Cytochrome b5 outer mi...	8.0E-45	[1..146]	[1..146]
gi\|83921614, gi\|... - gi\|83921614\|ref\|NP_085056.2\| cytochrome b5 outer mitochondrial membrane precursor [Homo sapiens], gi... gi\|55644113 - gi\|55644113\|ref\|XP_511067.1\| PREDICTED: hypothetical protein LOC454202 isoform 4 [Pan troglodytes]	9.0E-45	[1..146]	[5..150]
gi\|109129050 - gi\|109129050\|ref\|XP_001100954.1\| PREDICTED: similar to Cytochrome b5 outer mitochondrial membrane is...	3.0E-44	[1..146]	[5..150]
gi\|55726804 - gi\|55726804\|emb\|CAH90162.1\| hypothetical protein [Pongo abelii] gi\|197099436 - gi\|197099436\|ref\|NP_001125049.1\| cytochrome b5 type B (outer mitochondrial membrane) [Pongo abelii]	5.0E-44	[1..146]	[5..150]
CYB5B_RAT - Cytochrome b5 type B OS=Rattus norvegicus GN=Cyb5b PE=1 SV=2	1.0E-42	[1..146]	[1..146]
gi\|76640228 - gi\|76640228\|ref\|XP_582806.2\| PREDICTED: cytochrome b5 type B (outer mitochondrial membrane) [Bos tau...	3.0E-42	[1..146]	[92..237]
gi\|73957444 - gi\|73957444\|ref\|XP_853630.1\| PREDICTED: similar to cytochrome b5 outer mitochondrial membrane precur...	3.0E-42	[1..146]	[1..146]
gi\|74225098 - gi\|74225098\|dbj\|BAE38245.1\| unnamed protein product [Mus musculus]	1.0E-41	[1..146]	[1..146]

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Predicted Domain #1

Region A:
Residues: [1-146]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATAEASGSD GKGQEVETSV TYYRLEEVAK RNSLKELWLV IHGRVYDVTR FLNEHPGGEE  60
   61 VLLEQAGVDA SESFEDVGHS SDAREMLKQY YIGDIHPSDL KPESGSKDPS KNDTCKSCWA 120
  121 YWILPIIGAV LLGFLYRYYT SESKSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	1eueA
Description:	Cytochrome b5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2.29500061324594	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1.83295508128013	bayes_pls_golite062009
binding	0.901085034285767	bayes_pls_golite062009
monooxygenase activity	0.888525514618248	bayes_pls_golite062009
oxidoreductase activity	0.850524633890514	bayes_pls_golite062009
electron carrier activity	0.775128726876733	bayes_pls_golite062009
protein binding	0.391553538500747	bayes_pls_golite062009
steroid binding	0.177535173083536	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: