YRC Public Data Repository - Protein Structure Prediction

Protein:	TMEM19
Organism:	Homo sapiens
Length:	336 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TMEM19.

Description	E-value	Query Range	Subject Range
TMM19_PONAB - Transmembrane protein 19 OS=Pongo abelii GN=TMEM19 PE=2 SV=1 TMM19_PONPY - Transmembrane protein 19 - Pongo pygmaeus (Orangutan)	0.0	[1..336]	[1..336]
gi\|114645855, gi... - gi\|114645857\|ref\|XP_001158431.1\| PREDICTED: transmembrane protein 19 isoform 2 [Pan troglodytes], gi...	0.0	[1..336]	[1..336]
gi\|109097794, gi... - gi\|109097796\|ref\|XP_001117516.1\| PREDICTED: similar to transmembrane protein 19 isoform 2 [Macaca mu...	0.0	[1..336]	[1..336]
gi\|62897857 - gi\|62897857\|dbj\|BAD96868.1\| transmembrane protein 19 variant [Homo sapiens]	0.0	[1..336]	[1..336]
gi\|74223844 - gi\|74223844\|dbj\|BAE23820.1\| unnamed protein product [Mus musculus]	0.0	[1..335]	[1..335]
gi\|155372093, gi... - gi\|76660719\|ref\|XP_870916.1\| PREDICTED: hypothetical protein isoform 3 [Bos taurus], gi\|155372093\|re...	0.0	[1..335]	[1..335]
TMM19_XENTR - Transmembrane protein 19 OS=Xenopus tropicalis GN=tmem19 PE=2 SV=1	0.0	[1..335]	[1..335]

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Predicted Domain #1

Region A:
Residues: [1-200]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDLNDNICK RYIKMITNIV ILSLIICISL AFWIISMTAS TYYGNLRPIS PWRWLFSVVV  60
   61 PVLIVSNGLK KKSLDHSGAL GGLVVGFILT IANFSFFTSL LMFFLSSSKL TKWKGEVKKR 120
  121 LDSEYKEGGQ RNWVQVFCNG AVPTELALLY MIENGPGEIP VDFSKQYSAS WMCLSLLAAL 180
  181 ACSAGDTWAS EVGPVLSKSS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [201-336]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRLITTWEKV PVGTNGGVTV VGLVSSLLGG TFVGIAYFLT QLIFVNDLDI SAPQWPIIAF  60
   61 GGLAGLLGSI VDSYLGATMQ YTGLDESTGM VVNSPTNKAR HIAGKPILDN NAVNLFSSVL 120
  121 IALLLPTAAW GFWPRG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits