YRC Public Data Repository - Protein Structure Prediction

Protein:	DERL1
Organism:	Homo sapiens
Length:	251 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DERL1.

Description	E-value	Query Range	Subject Range
gi\|50758070 - gi\|50758070\|ref\|XP_415746.1\| PREDICTED: similar to carcinoma related gene [Gallus gallus]	9.0E-73	[5..249]	[128..359]
gi\|90075830 - gi\|90075830\|dbj\|BAE87595.1\| unnamed protein product [Macaca fascicularis] gi\|109087363 - gi\|109087363\|ref\|XP_001099154.1\| PREDICTED: similar to Der1-like domain family, member 1 isoform 2 [... CCDS6337.1_1 - null	1.0E-64	[1..251]	[1..251]
DERL1_PONPY - Derlin-1 - Pongo pygmaeus (Orangutan) DERL1_PONAB - Derlin-1 OS=Pongo abelii GN=DERL1 PE=2 SV=1	1.0E-64	[1..251]	[1..251]
gi\|73974576 - gi\|73974576\|ref\|XP_532320.2\| PREDICTED: similar to Der1-like domain family, member 1 [Canis familiar...	2.0E-64	[1..251]	[1..251]
DERL1_BOVIN - Derlin-1 OS=Bos taurus GN=DERL1 PE=2 SV=1	2.0E-64	[1..251]	[1..251]
DERL1_MOUSE - Derlin-1 OS=Mus musculus GN=Derl1 PE=1 SV=1 gi\|62652445, gi\|... - gi\|62652445\|ref\|XP_576271.1\| PREDICTED: similar to Der1-like domain family, member 1 [Rattus norvegi...	5.0E-64	[1..251]	[1..251]
gi\|54639131, gi\|... - gi\|54639131\|gb\|EAL28533.1\| GA13336-PA [Drosophila pseudoobscura], gi\|125776769\|ref\|XP_001359387.1\| G...	1.0E-62	[1..228]	[1..227]

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Predicted Domain #1

Region A:
Residues: [1-194]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDIGDWFRS IPAITRYWFA ATVAVPLVGK LGLISPAYLF LWPEAFLYRF QIWRPITATF  60
   61 YFPVGPGTGF LYLVNLYFLY QYSTRLETGA FDGRPADYLF MLLFNWICIV ITGLAMDMQL 120
  121 LMIPLIMSVL YVWAQLNRDM IVSFWFGTRF KACYLPWVIL GFNYIIGGSV INELIGNLVG 180
  181 HLYFFLMFRY PMDL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.221849
Match:	2ic8A
Description:	No description for 2ic8A was found.

Predicted Domain #2

Region A:
Residues: [195-251]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGRNFLSTPQ FLYRWLPSRR GGVSGFGVPP ASMRRAADQN GGGGRHNWGQ GFRLGDQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.270	N/A	N/A	a.144.2	Ribosomal protein L20
View	Download	0.234	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.222	N/A	N/A	a.24.13	Domain of the SRP/SRP receptor G-proteins

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits