YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|12654285
Organism:	Homo sapiens
Length:	633 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|12654285.

Description	E-value	Query Range	Subject Range
NGLY1 - N-glycanase 1 gi\|123993667, gi... - gi\|123999983\|gb\|ABM87500.1\| N-glycanase 1 [synthetic construct], gi\|123993667\|gb\|ABM84435.1\| N-glyca...	0.0	[16..633]	[19..654]
NGLY1_MACFA - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Macaca fascicularis GN=NGLY1 PE=2 SV=...	0.0	[16..633]	[19..654]
gi\|109052533 - gi\|109052533\|ref\|XP_001093251.1\| PREDICTED: similar to N-glycanase 1 isoform 4 [Macaca mulatta]	0.0	[16..633]	[19..654]
gi\|114586207 - gi\|114586207\|ref\|XP_516333.2\| PREDICTED: hypothetical protein [Pan troglodytes]	0.0	[16..633]	[218..835]
gi\|8347622, gi\|1... - gi\|8347622\|gb\|AAF74723.1\|AF250927_1 PNGase [Mus musculus], gi\|30517852\|gb\|AAP03060.1\| peptide N-glyc...	0.0	[16..633]	[19..651]
NGLY1_RAT - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Rattus norvegicus GN=Ngly1 PE=2 SV=2	0.0	[16..633]	[19..651]
gi\|76656037 - gi\|76656037\|ref\|XP_613238.2\| PREDICTED: similar to N-glycanase 1 [Bos taurus]	0.0	[2..633]	[116..766]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AALGSSSGSA SPAVAELCQN TPETFLEASK LLLTYADNIL RNPNDEKYRS IRIGNTAFST  60
   61 RLLPVRGAVE CLFEMGFEEG ETHLIFPKKA SVEQLQKIRD LIAIERSSRL DGSNKSHKVK 120
  121 SSQQPAASTQ LPTTPSSNPS GLNQHTRNRQ GQSSDPPS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.221849
Match:	2ccqA
Description:	No description for 2ccqA was found.

Predicted Domain #2

Region A:
Residues: [159-432]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASTVAADSAI LEVLQSNIQH VLVYENPALQ EKALACIPVQ ELKRKSQEKL SRARKLDKGI  60
   61 NISDEDFLLL ELLHWFKEEF FHWVNNVLCS KCGGQTRSRD RSLLPSDDEL KWGAKEVEDH 120
  121 YCDACQFSNR FPRYNNPEKL LETRCGRCGE WANCFTLCCR AVGFEARYVW DYTELQRTLS 180
  181 LKLTTLKEIG KTFLRISKRQ KLIQVVDVTW RYSCKHEEVI ARRTKVKEAL LRDTINGLNK 240
  241 QRQLFLSENR RKELLQRIIV ELVEFISPKT PKPG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	112.0
Match:	2f4mA
Description:	The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [433-633]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELGGRISGSV AWRVARGEMG LQRKETLFIP CENEKISKQL HLCYNIVKDR YVRVSNNNQT  60
   61 ISGWENGVWK MESIFRKVET DWHMVYLARK EGSSFAYISW KFECGSVGLK VDSISIRTSS 120
  121 QTFQTGTVEW KLRSDTAQVE LTGDNSLHSY ADFSGATEVI LEAELSRGDG DVAWQHTQLF 180
  181 RQSLNDHEEN CLEIIIKFSD L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.39794
Match:	2g9gA
Description:	No description for 2g9gA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits