| Protein: | TLX2 |
| Organism: | Homo sapiens |
| Length: | 284 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TLX2.
| Description | E-value | Query Range |
Subject Range |
|
|
7.0E-31 | [1..284] | [1..284] |
|
|
1.0E-30 | [1..284] | [1..284] |
|
|
3.0E-30 | [7..279] | [6..298] |
|
|
7.0E-30 | [1..284] | [1..284] |
|
|
2.0E-29 | [1..284] | [1..284] |
|
|
3.0E-29 | [1..284] | [1..284] |
|
|
1.0E-28 | [17..229] | [2..224] |
|
Region A: Residues: [1-140] |
1 11 21 31 41 51
| | | | | |
1 MEPGMLGPHN LPHHEPISFG IDQILSGPET PGGGLGLGRG GQGHGENGAF SGGYHGASGY 60
61 GPAGSLAPLP GSSGVGPGGV IRVPAHRPLP VPPPAGGAPA VPGPSGLGGA GGLAGLTFPW 120
121 MDSGRRFAKD RLTAALSPFS
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [141-284] |
1 11 21 31 41 51
| | | | | |
1 GTRRIGHPYQ NRTPPKRKKP RTSFSRSQVL ELERRFLRQK YLASAERAAL AKALRMTDAQ 60
61 VKTWFQNRRT KWRRQTAEER EAERHRAGRL LLHLQQDALP RPLRPPLPPD PLCLHNSSLF 120
121 ALQNLQPWAE DNKVASVSGL ASVV
|
| Detection Method: | |
| Confidence: | 27.522879 |
| Match: | 1homA |
| Description: | DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
| chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| protein binding | 0.830419844171551 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
