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View Structure Prediction Details

Protein: SSP1A_ORYSA
Organism: Oryza sativa
Length: 641 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSP1A_ORYSA.

Description E-value Query
Range
Subject
Range
gi|116283314 - gi|116283314|gb|AAH04848.1| Ssrp1 protein [Mus musculus]
718.0 [0..1] [624..1]

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Predicted Domain #1
Region A:
Residues: [1-161]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDGHLFNNI LLGGRAGSNP GQFKVYSGGL AWKRQGGGKT IEIEKSDLTS VTWMKVPRAY  60
   61 QLGVRTKDGL FYKFIGFREQ DVSSLTNFMQ KNMGLSPDEK QLSVSGQNWG GIDINGNMLT 120
  121 FMVGSKQAFE VSLADVSQTQ MQGKTDVLLE FHVDDTTGGN E

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [162-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDSLMDLSFH VPTSNTQFLG DENRTAAQVL WETIMGVADV DSSEEAVVTF EGIAILTPRG  60
   61 RYSVELHLSF LRLQGQANDF KIQYSSIVRL FLLPKSNNPH TFVVVTLDPP IRKGQTLYPH 120
  121 IVIQFETEAV VERNLALTKE VLAEKYKDRL EESYKGLIHE VFTKVLRGLS GAKVTRPGSF 180
  181 RSCQDGYAVK SSLKAEDGLL YPLEKGFFFL PKPPTLILHE EIEFVEFERH GAGGASISSH 240
  241 YFDLLVKLKN DQEHLFRNIQ RSEYHNLFNF INGKHLKIMN LGDGQGATGG VTAVLRDTDD 300
  301 DAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.522879
Match: 2gcjA
Description: No description for 2gcjA was found.

Predicted Domain #3
Region A:
Residues: [465-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPHLERIKNQ AGDEESDEED EDFVADKDDS GSPTDDSGGE DSDASESGGE KEKLSKKEAS  60
   61 SSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [528-641]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPVKRKPKGR DEEGSDKRKP KKKKDPNAPK RAMTPFMYFS MAERGNMKNN NPDLPTTEIA  60
   61 KKLGEMWQKM TGEEKQPYIQ QSQVDKKRYE KESAVYRGAA AMDVDSGSGG NESD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.30103
Match: 1o4xB
Description: TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 5.15324651287773 bayes_pls_golite062009
nucleic acid binding 5.01228762819617 bayes_pls_golite062009
transcription regulator activity 4.9607192917135 bayes_pls_golite062009
transcription factor activity 3.82658263870186 bayes_pls_golite062009
binding 3.6211482127468 bayes_pls_golite062009
transcription repressor activity 3.17018042329608 bayes_pls_golite062009
sequence-specific DNA binding 2.96229555092695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.75319687398598 bayes_pls_golite062009
transcription activator activity 1.62744929149746 bayes_pls_golite062009
structure-specific DNA binding 1.51189746794562 bayes_pls_golite062009
protein binding 1.131658134984 bayes_pls_golite062009
transcription factor binding 1.10315330167937 bayes_pls_golite062009
chromatin binding 0.996049314969019 bayes_pls_golite062009
DNA bending activity 0.87985209274756 bayes_pls_golite062009
specific transcriptional repressor activity 0.4255419067266 bayes_pls_golite062009
single-stranded DNA binding 0.392549154964715 bayes_pls_golite062009
open form four-way junction DNA binding 0.293183929205961 bayes_pls_golite062009
bent DNA binding 0.293183929205961 bayes_pls_golite062009
crossed form four-way junction DNA binding 0.293183929205961 bayes_pls_golite062009
DNA secondary structure binding 0.18003196535795 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.0654173145582195 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle