YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: PRKCD
Organism: Homo sapiens
Length: 676 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRKCD.

Description E-value Query
Range
Subject
Range
gi|33304013 - gi|33304013|gb|AAQ02514.1| protein kinase C, delta [synthetic construct]
0.0 [1..676] [1..676]
PRKCD - protein kinase C, delta
0.0 [1..676] [1..676]
gi|76678717 - gi|76678717|ref|XP_582038.2| PREDICTED: similar to protein kinase C, delta isoform 1 [Bos taurus]
0.0 [1..676] [1..668]
gi|109039102 - gi|109039102|ref|XP_001083320.1| PREDICTED: similar to protein kinase C, delta [Macaca mulatta]
0.0 [37..676] [501..1140]

Back

Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPFLRIAFN SYELGSLQAE DEANQPFCAV KMKEALSTER GKTLVQKKPT MYPEWKSTFD  60
   61 AHIYEGRVIQ IVLMRAAEEP VSEVTVGVSV LAERCKKNNG KAEFWLDLQP QAKVLMSVQY 120
  121 FL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1yrkA
Description: The C2 Domain of PKC is a new Phospho-Tyrosine Binding Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [123-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDVDCKQSMR SEDEAKFPTM NRRGAIKQAK IHYIKNHEFI ATFFGQPTFC SVCKDFVWGL  60
   61 NKQGYKCRQC NAAIHKKCID KIIGRCTGTA ANSRDTIFQK ERFNIDMPHR FKVHNYMSPT 120
  121 FCDHCGSLLW GLVKQGLKCE DCGMNVHHKC REKVANLCGI NQKLLAEALN QVTQRASRRS 180
  181 DSASSEPVGI YQGFEKKTGV AGEDMQDNSG TYGKIWEGSS KCNINNFIFH KVLGKGSFGK 240
  241 VLLGELKGRG EYFAIKALKK DVVLIDDDVE CTMVEKRVLT LAAENPFLTH LICTFQTKDH 300
  301 LFFVMEFLNG GDLMYHIQDK GRFELYRATF YAAEIMCGLQ FLHSKGIIYR DLKLDNVLLD 360
  361 RDGHIKIADF GMCKENIFGE SRASTFCGTP DYIAPEILQG LKYTFSVDWW SFGVLLYEML 420
  421 IGQSPFHGDD EDELFESIRV DTPHYPRWIT KESKDILEKL FEREPTKRLG VTGNIKIHPF 480
  481 FKTINWTLLE K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.221849
Match: 2ozoA
Description: No description for 2ozoA was found.

Predicted Domain #3
Region A:
Residues: [614-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRLEPPFRPK VKSPRDYSNF DQEFLNEKAR LSYSDKNLID SMDQSAFAGF SFVNPKFEHL  60
   61 LED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.522879
Match: 1xjdA
Description: Crystal Structure of PKC-theta complexed with Staurosporine at 2A resolution
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle