YRC Public Data Repository - Protein Structure Prediction

Protein:	NUD15_MOUSE
Organism:	Mus musculus
Length:	170 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUD15_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|149049947, gi... - gi\|27701910\|ref\|XP_214236.1\| PREDICTED: similar to MTH2 protein [Rattus norvegicus], gi\|157823211\|re...	135.0	[0..1]	[170..1]
gi\|94366446, gi\|... - gi\|94368225\|ref\|XP_994694.1\| PREDICTED: similar to MTH2 protein [Mus musculus], gi\|94366446\|ref\|XP_9...	131.0	[0..1]	[170..1]
gi\|113942320, gi... - gi\|113942320\|ref\|ZP_01428055.1\| NUDIX hydrolase [Herpetosiphon aurantiacus ATCC 23779], gi\|113896038...	119.0	[0..5]	[155..5]
gi\|106892416, gi... - gi\|148654328\|ref\|YP_001274533.1\| NUDIX hydrolase [Roseiflexus sp. RS-1], gi\|148566438\|gb\|ABQ88583.1\|...	118.0	[0..5]	[155..14]
ADPP_METJA - ADP-ribose pyrophosphatase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / ... ADPP_METJA - ADP-ribose pyrophosphatase OS=Methanocaldococcus jannaschii GN=nudF PE=1 SV=1	117.0	[0..3]	[146..33]
NUDT15 - nudix (nucleoside diphosphate linked moiety X)-type motif 15 gi\|55633687, gi\|... - gi\|55633687\|ref\|XP_521439.1\| PREDICTED: hypothetical protein [Pan troglodytes], gi\|114649585\|ref\|XP_...	117.0	[0..22]	[163..23]
gi\|30314626 - gi\|30314626\|dbj\|BAC76070.1\| Nudix hydrolase [Synechococcus sp. PCC 7002]	117.0	[0..8]	[154..7]

Back

Predicted Domain #1

Region A:
Residues: [1-170]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAANAEPRRR PGVGVGVVVL SCEHPRCVLL GKRKGSFGAG SFQLPGGHLE FGETWEECAQ  60
   61 RETWEEAGLH LKNVCFASVV NSFVEKENYH YVTILMKGEV DMTHDSEPRN MEPEKNESWE 120
  121 WVPWEEFPPL DQLFWALRCL KEQGYDPFKE DLNHLEGYRG EHLERTTKTP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.0
Match:	2fmlA
Description:	Crystal structure of MutT/nudix family protein from Enterococcus faecalis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.49075808737475	bayes_pls_golite062009
MutLbeta complex binding	1.22969197985984	bayes_pls_golite062009
MutSbeta complex binding	1.22969197985984	bayes_pls_golite062009
hydrolase activity	0.911224605592679	bayes_pls_golite062009
cation transmembrane transporter activity	0.764902549171301	bayes_pls_golite062009
ion transmembrane transporter activity	0.708899614527609	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.579896508304411	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.537695290728274	bayes_pls_golite062009
substrate-specific transporter activity	0.530568650884674	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: