Protein: | Dscam-PBC |
Organism: | Drosophila melanogaster |
Length: | 2030 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PBC.
Description | E-value | Query Range |
Subject Range |
|
1548.0 | [0..3] | [2030..3] |
Region A: Residues: [1-138] |
1 11 21 31 41 51 | | | | | | 1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60 61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120 121 NQFGSIISRD VHVRAVVK |
Detection Method: | |
Confidence: | 78.154902 |
Match: | 2v5sA |
Description: | No description for 2v5sA was found. |
Region A: Residues: [139-244] |
1 11 21 31 41 51 | | | | | | 1 QFFESQVYDE YVIKGNAAIF KCQTPSFVAD HIDITDWIDT EGEVFTKNIT DGKYLVLPSG 60 61 ELHIREVGPE DGYKSYQCRT KHRLTGETRL SATKGRLVIT EPIGSV |
Detection Method: | |
Confidence: | 11.0 |
Match: | 1f3rB |
Description: | Immunoglobulin light chain kappa variable domain, VL-kappa; Immunoglobulin heavy chain variable domain, VH |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
telethonin binding | 6.64811984458494 | bayes_pls_golite062009 |
alpha-actinin binding | 5.77350124471385 | bayes_pls_golite062009 |
actinin binding | 5.69539760434923 | bayes_pls_golite062009 |
structural constituent of muscle | 4.93896503565413 | bayes_pls_golite062009 |
olfactory receptor activity | 4.21057154107121 | bayes_pls_golite062009 |
antigen binding | 4.06466268219034 | bayes_pls_golite062009 |
receptor activity | 4.00123250685257 | bayes_pls_golite062009 |
transmembrane receptor activity | 3.81769911097805 | bayes_pls_golite062009 |
binding | 3.17641566810715 | bayes_pls_golite062009 |
signal transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
molecular transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
peptide antigen binding | 2.94721224577771 | bayes_pls_golite062009 |
fibroblast growth factor 1 binding | 2.83860944503193 | bayes_pls_golite062009 |
growth factor binding | 2.28613301180608 | bayes_pls_golite062009 |
protein binding | 2.22855404705168 | bayes_pls_golite062009 |
extracellular matrix structural constituent | 1.97667893885412 | bayes_pls_golite062009 |
IgG binding | 1.92633562075074 | bayes_pls_golite062009 |
receptor binding | 1.70260377709721 | bayes_pls_golite062009 |
cytoskeletal protein binding | 1.58610597245454 | bayes_pls_golite062009 |
transmembrane receptor protein tyrosine kinase activity | 1.52958974617075 | bayes_pls_golite062009 |
actin binding | 1.42681407553255 | bayes_pls_golite062009 |
cell adhesion molecule binding | 1.36789541796983 | bayes_pls_golite062009 |
protein kinase activity | 1.36635494500222 | bayes_pls_golite062009 |
nucleic acid binding | 1.32330470851159 | bayes_pls_golite062009 |
transmembrane receptor protein kinase activity | 1.30657787244536 | bayes_pls_golite062009 |
fibroblast growth factor binding | 1.27793818082552 | bayes_pls_golite062009 |
fibroblast growth factor receptor activity | 1.24730237107473 | bayes_pls_golite062009 |
DNA binding | 1.19412627500732 | bayes_pls_golite062009 |
myosin light chain kinase activity | 1.17845072849922 | bayes_pls_golite062009 |
transcription regulator activity | 1.16252234499274 | bayes_pls_golite062009 |
G-protein coupled receptor activity | 1.02428106476324 | bayes_pls_golite062009 |
phosphotransferase activity, alcohol group as acceptor | 1.02286631988334 | bayes_pls_golite062009 |
kinase activity | 0.929878054374821 | bayes_pls_golite062009 |
transferase activity, transferring phosphorus-containing groups | 0.878595022643164 | bayes_pls_golite062009 |
protein complex binding | 0.83543827718565 | bayes_pls_golite062009 |
actin filament binding | 0.760856470721016 | bayes_pls_golite062009 |
peptide binding | 0.729048089532569 | bayes_pls_golite062009 |
collagen binding | 0.635057461053063 | bayes_pls_golite062009 |
cytokine binding | 0.631436442105379 | bayes_pls_golite062009 |
titin binding | 0.599892148302011 | bayes_pls_golite062009 |
integrin binding | 0.599569390248921 | bayes_pls_golite062009 |
structural molecule activity | 0.567620977360967 | bayes_pls_golite062009 |
protein serine/threonine kinase activity | 0.564762108830441 | bayes_pls_golite062009 |
transcription factor activity | 0.54549168007511 | bayes_pls_golite062009 |
myosin heavy chain binding | 0.49788128784685 | bayes_pls_golite062009 |
cytokine receptor activity | 0.34165331857492 | bayes_pls_golite062009 |
protein tyrosine kinase activity | 0.318890055375093 | bayes_pls_golite062009 |
structural constituent of cytoskeleton | 0.0579247757286607 | bayes_pls_golite062009 |
Region A: Residues: [245-908] |
1 11 21 31 41 51 | | | | | | 1 PPKITSLHDK FQVLQVKLAE DFSMQCPGQA YPVPIVRWYK FIEGTTRKQA VVLNDRVKQV 60 61 SGTLIIKDAV VEDSGKYLCV VNNSVGGESV ETVLTVTAPL SAKIDPPTQT VDFGRPAVFT 120 121 CQYTGNPIKT VSWMKDGKAI GHSEPVLRIE SVKKEDKGMY QCFVRNDQES AEASAELKLG 180 181 GRFDPPVIRQ AFQEETMEPG PSVFLKCVAG GNPTPEISWE LDGKKIANND RYQVGQYVTV 240 241 NGDVVSYLNI TSVHANDGGL YKCIAKSKVG VAEHSAKLNV YGLPYIRQME KKAIVAGETL 300 301 IVTCPVAGYP IDSIVWERDN RALPINRKQK VFPNGTLIIE NVERNSDQAT YTCVAKNQEG 360 361 YSARGSLEVQ VMVPPKLAPL PVNSPLYVGD YYQLTCAVVH GDAPFNITWY YNNEPAGDLA 420 421 GVTILMHGRR SSSLNIESVG GDHAGNYTCK GANRAGETTA ETHLSVKVPP RWILEPTDKA 480 481 FAQGSDAKVE CKADGFPKPQ VTWKKAVGDT PGEYKDLKKS DNIRVEEGTL HVDNIQKTNE 540 541 GYYLCEAING IGSGLSAVIM ISVQAPPEFT EKLRNQTARR GEPAVLQCEA KGEKPIGILW 600 601 NMNNMRLDPK NDNRYTIREE ILSTGVMSSL SIKRTERSDS ALFTCVATNA FGSDDASINM 660 661 IVQE |
Detection Method: | |
Confidence: | 58.30103 |
Match: | 1e07A |
Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [909-1003] |
1 11 21 31 41 51 | | | | | | 1 VPEMPYALKV LDKSGRSVQL SWAQPYDGNS PLDRYIIEFK RSRASWSEID RVIVPGHTTE 60 61 AQVQKLSPAT TYNIRIVAEN AIGTSQSSEA VTIIT |
Detection Method: | |
Confidence: | 35.69897 |
Match: | 2nziA |
Description: | No description for 2nziA was found. |
Region A: Residues: [1004-1101] |
1 11 21 31 41 51 | | | | | | 1 AEEAPSGKPQ NIKVEPVNQT TMRVTWKPPP RTEWNGEILG YYVGYKLSNT NSSYVFETIN 60 61 FITEEGKEHN LELQNLRVYT QYSVVIQAFN KIGAGPLS |
Detection Method: | |
Confidence: | 12.69897 |
Match: | 1va9A |
Description: | Solution structure of the second FNIII domain of DSCAML1 protein |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
extracellular matrix structural constituent | 3.5949595622742 | bayes_pls_golite062009 |
protein binding | 3.24522318184038 | bayes_pls_golite062009 |
binding | 3.12471204223368 | bayes_pls_golite062009 |
receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
growth hormone receptor activity | 1.94500909454564 | bayes_pls_golite062009 |
mercury ion binding | 1.85843060232985 | bayes_pls_golite062009 |
cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
actin binding | 1.21472460452555 | bayes_pls_golite062009 |
DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
interleukin-6 receptor activity | 0.888638861691021 | bayes_pls_golite062009 |
interleukin-6 binding | 0.888638861691021 | bayes_pls_golite062009 |
protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
pattern binding | 0.44460010885883 | bayes_pls_golite062009 |
growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
protease binding | 0.12595904253108 | bayes_pls_golite062009 |
protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
Region A: Residues: [1102-1212] |
1 11 21 31 41 51 | | | | | | 1 EEEKQFTAEG TPSQPPSDTA CTTLTSQTIR VGWVSPPLES ANGVIKTYKV VYAPSDEWYD 60 61 ETKRHYKKTA SSDTVLHGLK KYTNYTMQVL ATTAGGDGVR SVPIHCQTEP D |
Detection Method: | |
Confidence: | 20.522879 |
Match: | 1qg3A |
Description: | Integin beta-4 subunit |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [1213-1309] |
1 11 21 31 41 51 | | | | | | 1 VPEAPTDVKA LVMGNAAILV SWRPPAQPNG IITQYTVYSK AEGAETETKT QKVPHYQMSF 60 61 EATELEKNKP YEFWVTASTT IGEGQQSKSI VAMPSDQ |
Detection Method: | |
Confidence: | 9.0 |
Match: | 1wfnA |
Description: | The fourth FN3 domain of human sidekick-2 |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [1310-1386] |
1 11 21 31 41 51 | | | | | | 1 VPAKIASFDD TFTATFKEDA KMPCLAVGAP QPEITWKIKG VEFSANDRMR VLPDGSLLIK 60 61 SVNRQDAGDY SCHAENS |
Detection Method: | |
Confidence: | 4.13 |
Match: | 2yr3A |
Description: | No description for 2yr3A was found. |
Region A: Residues: [1387-1493] |
1 11 21 31 41 51 | | | | | | 1 IAKDSITHKL IVLAPPQSPH VTLSATTTDA LTVKLKPHEG DTAPLHGYTL HYKPEFGEWE 60 61 TSEVSVDSQK HNIEGLLCGS RYQVYATGFN NIGAGEASDI LNTRTKG |
Detection Method: | |
Confidence: | 6.522879 |
Match: | 1x5iA |
Description: | The solution structure of the fourth fibronectin type III domain of human Neogenin |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
extracellular matrix structural constituent | 3.5949595622742 | bayes_pls_golite062009 |
protein binding | 3.24522318184038 | bayes_pls_golite062009 |
binding | 3.12471204223368 | bayes_pls_golite062009 |
receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
growth hormone receptor activity | 1.94500909454564 | bayes_pls_golite062009 |
mercury ion binding | 1.85843060232985 | bayes_pls_golite062009 |
cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
actin binding | 1.21472460452555 | bayes_pls_golite062009 |
DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
interleukin-6 receptor activity | 0.888638861691021 | bayes_pls_golite062009 |
interleukin-6 binding | 0.888638861691021 | bayes_pls_golite062009 |
protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
pattern binding | 0.44460010885883 | bayes_pls_golite062009 |
growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
protease binding | 0.12595904253108 | bayes_pls_golite062009 |
protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
Region A: Residues: [1494-1663] |
1 11 21 31 41 51 | | | | | | 1 QKPKLPEKPR FIEVSSNSVS LHFKAWKDGG CPMSHFVVES KKRDQIEWNQ ISNNVKPDNN 60 61 YVVLDLEPAT WYNLRITAHN SAGFTVAEYD FATLTVTGGT IAPLDDGSGH GNVHTRIRLP 120 121 AWMPEWLDLN FMVPLIATVV VVAVGICVVC VALSRRRADD MRGGQKDVYY |
Detection Method: | |
Confidence: | 24.154902 |
Match: | 2v5yA |
Description: | No description for 2v5yA was found. |
Region A: Residues: [1664-1841] |
1 11 21 31 41 51 | | | | | | 1 DVVYNQTMGP GATLDKRRPD LRDELGYIAP PNRKLPPVPG SNYNTCDRIK RGRGGLRSNH 60 61 STWDPRRNPN LYEELKAPPV PMHGNHYGHA HGNAECHYRH PGMEDEICPY ATFHLLGFRE 120 121 EMDPTKAMNF QTFPHQNGHA GPVPGHAGTM LPPGHPGHVH SRSGSQSMPR ANRYQRKN |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [1842-2030] |
1 11 21 31 41 51 | | | | | | 1 SQGGQSSIYT PAPEYDDPAN CAEEDQYRRY TRVNSQGGSL YSGPGPEYDD PANCAPEEDQ 60 61 YGSQYGGPYG QPYDHYGSRG SMGRRSIGSA RNPGNGSPEP PPPPPRNHDM SNSSFNDSKE 120 121 SNEISEAECD RDHGPRGNYG AVKRSPQPKD QRTTEEMRKL IERNETGPKQ LQLQQANGAG 180 181 FTAYDTMAV |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.