YRC Public Data Repository - Protein Structure Prediction

Protein:	GUC2A_MOUSE
Organism:	Mus musculus
Length:	116 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GUC2A_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|114555875 - gi\|114555875\|ref\|XP_001172840.1\| PREDICTED: similar to guanylin isoform 2 [Pan troglodytes]	175.0	[0..1]	[116..1]
gi\|162319024, gi... - gi\|162319024\|gb\|AAI56567.1\| Guanylate cyclase activator 2A (guanylin) [synthetic construct], gi\|1478... GUCA2A - guanylate cyclase activator 2A (guanylin)	174.0	[0..1]	[116..1]
GUC2A_NOTAL - Guanylin OS=Notomys alexis GN=GUCA2A PE=3 SV=1	168.0	[0..1]	[116..1]
GUC2A_RAT - Guanylin OS=Rattus norvegicus GN=Guca2a PE=1 SV=1	167.0	[0..1]	[116..1]
gi\|1835224 - gi\|1835224\|emb\|CAA97974.1\| GCAP-I/guanylin precursor [Sus scrofa domestica] GUC2A_PIG - Guanylin OS=Sus scrofa GN=GUCA2A PE=3 SV=1	157.0	[0..1]	[116..1]
gi\|109003241 - gi\|109003241\|ref\|XP_001085421.1\| PREDICTED: similar to guanylate cyclase activator 2A [Macaca mulatt...	155.0	[0..15]	[116..15]
GUC2A_CAVPO - Guanylin OS=Cavia porcellus GN=GUCA2A PE=3 SV=1	150.0	[0..1]	[116..1]
gi\|73976735 - gi\|73976735\|ref\|XP_539563.2\| PREDICTED: similar to guanylate cyclase activator 2A [Canis familiaris]	148.0	[0..1]	[116..454]
gi\|76615300 - gi\|76615300\|ref\|XP_610296.2\| PREDICTED: similar to guanylin [Bos taurus]	144.0	[0..1]	[116..1]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNACVLSVLC LLGALAVLVE GVTVQDGDLS FPLESVKKLK GLREVQEPRL VSHKKFAPRL  60
   61 LQPVAPQLCS SHSALPEALR PVCEKPNAEE ILQRLEAIAQ DPNTCEICAY AACTGC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.39794
Match:	1o8rA
Description:	Proguanylin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits