YRC Public Data Repository - Protein Structure Prediction

Protein:	TRMB_STRPD
Organism:	Streptococcus pyogenes MGAS10270
Length:	211 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRMB_STRPD.

Description	E-value	Query Range	Subject Range
TRMB_STRPJ - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1... TRMB_STRZP - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain P1031) GN=trmB PE=3 SV=1 TRMB_STRPI - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain Hungary19A-6) GN=trmB PE=... gi\|237650177 - gi\|237650177\|ref\|ZP_04524429.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CCR... gi\|237821777 - gi\|237821777\|ref\|ZP_04597622.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CCR... gi\|147930202, gi... - gi\|149021506\|ref\|ZP_01835561.1\| tRNA (guanine-N(7))-methyltransferase [Streptococcus pneumoniae SP23... TRMB_STRPN - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae GN=trmB PE=1 SV=1 gi\|147763380, gi... - gi\|149012575\|ref\|ZP_01833572.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae SP1... gi\|149005661, gi... - gi\|149005661\|ref\|ZP_01829400.1\| tRNA (guanine-N(7))-methyltransferase [Streptococcus pneumoniae SP18... TRMB_STRR6 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) GN=trm... gi\|149002222, gi... - gi\|149002222\|ref\|ZP_01827164.1\| tRNA (guanine-N(7))-methyltransferase [Streptococcus pneumoniae SP14... gi\|183573082, gi... - gi\|183573082\|gb\|EDT93610.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae SP195],... gi\|168485662, gi... - gi\|183571191\|gb\|EDT91719.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CDC1087... gi\|183576911, gi... - gi\|183576911\|gb\|EDT97439.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CDC3059... gi\|168490559, gi... - gi\|183574963\|gb\|EDT95491.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CDC0288... gi\|147928965, gi... - gi\|148992339\|ref\|ZP_01822062.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae SP9... TRMB_STRP2 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 746... TRMB_STRPN - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 /... TRMB_STRZJ - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain JJA) GN=trmB PE=3 SV=1	173.0	[0..1]	[211..1]

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Predicted Domain #1

Region A:
Residues: [1-211]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVRKRKGAE EHLANNPHYV ILNPEDAKGR WHDVFGNDRP IHIEVGSGKG GFITGMALKN  60
   61 PDINYIGIDI QLSVLSYALD KVLASEVPNV KLLRVDGSSL TNYFEDGEVD MMYLNFSDPW 120
  121 PKTKHEKRRL TYKDFLDTYK RILPEHGEIH FKTDNRGLFE YSLASFSQYG MTLRQIWLDL 180
  181 HASNYEGNVM TEYEEKFSNK GQVIYRVEAN F

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.69897
Match:	1yzhA
Description:	Crystal Structure of the Conserved Hypothetical Protein, Methyltransferase from Streptococcus pneumoniae TIGR4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.06737071331982	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.9962750833086	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.74830027382001	bayes_pls_golite062009
RNA methyltransferase activity	3.6174490060285	bayes_pls_golite062009
rRNA methyltransferase activity	2.80578045927127	bayes_pls_golite062009
transferase activity	2.42370637689376	bayes_pls_golite062009
tRNA methyltransferase activity	2.15176183511624	bayes_pls_golite062009
catalytic activity	1.62377578202456	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.72946673557525	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.62885479399246	bayes_pls_golite062009
N-methyltransferase activity	0.49575399394607	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	0.355378060639199	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: