YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|110807351, gi...
Organism:	Shigella flexneri 5 str. 8401
Length:	283 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|110807351, gi....

Description	E-value	Query Range	Subject Range
gi\|18652680\|gb\|A... - orfB in IS150 [Escherichia coli] gi\|18652680 - gi\|18652680\|gb\|AAB18535.2\| orfB in IS150 [Escherichia coli str. K-12 substr. MG1655]	207.0	[0..1]	[283..1]
gi\|170517665, gi... - gi\|170679947\|ref\|YP_001743153.1\| IS150 transposase orfB [Escherichia coli SMS-3-5], gi\|170517665\|gb\|... gi\|117624195, gi... - gi\|117624195\|ref\|YP_853108.1\| putative transposase subunit [Escherichia coli APEC O1], gi\|115513319\|...	204.0	[0..1]	[283..1]
gi\|30062890, gi\|... - gi\|30062890\|ref\|NP_837061.1\| IS103 orf [Shigella flexneri 2a str. 2457T], gi\|30041138\|gb\|AAP16868.1\|...	202.0	[0..1]	[283..1]
gi\|46242587 - gi\|46242587\|gb\|AAS83411.1\| putative transposase OCP [uncultured Ralstonia sp.]	200.0	[0..4]	[282..107]
gi\|75188988, gi\|... - gi\|75188988\|ref\|ZP_00702255.1\| COG2801: Transposase and inactivated derivatives [Escherichia coli E2... gi\|194437827, gi... - gi\|83586674\|ref\|ZP_00925306.1\| COG2801: Transposase and inactivated derivatives [Escherichia coli 10... gi\|218698131, gi... - gi\|218698131\|ref\|YP_002405798.1\| hypothetical protein EC55989_4948 [Escherichia coli 55989], gi\|2183...	195.0	[0..3]	[280..95]
gi\|110615289, gi... - gi\|110805741\|ref\|YP_689261.1\| IS600 ORF2 [Shigella flexneri 5 str. 8401], gi\|110615289\|gb\|ABF03956.1...	195.0	[0..3]	[280..97]
gi\|115365647, gi... - gi\|115377327\|ref\|ZP_01464534.1\| isrso8-transposase orfb protein [Stigmatella aurantiaca DW4/3-1], gi...	193.0	[0..2]	[279..4]

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Predicted Domain #1

Region A:
Residues: [1-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVLNELRQF YPLDELLRAA EIPRSTFYYH LKALSKPDKY ADVKKRIGEI YHENRGRYGY  60
   61 RRVTLSLHRE GKQINHKAVQ RLMGTLSLKA AIKVKRYRSY RGEVGQTAPN VLQRDFKATR 120
  121 PNEKWVTDVT EFAVNGRKLY LSPVIDLFNN EVISYSLSER PVMNMVENML DQAFKKLNPH 180
  181 EHPVLHSDQG WQYRMRRYQN ILKEHGIKQS MSRKGNCLDN AVVECFFGTL KSECFYLDEF 240
  241 SNISELKDAV TEYIEYYNSR RISLKLKGLT PIEYRNQTYM PRV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.69897
Match:	1k6yA
Description:	N-terminal Zn binding domain of HIV integrase; Retroviral integrase, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nuclease activity	1.81796593394339	bayes_pls_golite062009
exonuclease activity	1.64964907710028	bayes_pls_golite062009
catalytic activity	1.62277843225829	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.58702937619673	bayes_pls_golite062009
hydrolase activity	1.41857676124086	bayes_pls_golite062009
transposase activity	1.09803761537443	bayes_pls_golite062009
ribonuclease activity	0.71352601607444	bayes_pls_golite062009
deoxyribonuclease activity	0.63299586096139	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.62821439153618	bayes_pls_golite062009
endonuclease activity	0.150927275899469	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: