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View Structure Prediction Details

Protein: NMD2_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 1049 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NMD2_SCHPO.

Description E-value Query
Range
Subject
Range
gi|28923326, gi|... - gi|32408285|ref|XP_324624.1| hypothetical protein [Neurospora crassa], gi|28923326|gb|EAA32521.1| hy...
gi|85104544 - gi|85104544|ref|XP_961757.1| hypothetical protein [Neurospora crassa OR74A]
1048.0 [0..10] [1049..3]
gi|38106654, gi|... - gi|39976021|ref|XP_369401.1| hypothetical protein MG06063.4 [Magnaporthe grisea 70-15], gb|EAA52935....
1039.0 [0..10] [1049..3]
gi|46110132, gi|... - gi|46110132|ref|XP_382124.1| hypothetical protein FG01948.1 [Gibberella zeae PH-1], gi|42546001|gb|E...
1028.0 [0..10] [1049..3]
gi|49100079, gi|... - gi|67541050|ref|XP_664299.1| hypothetical protein AN6695.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
1007.0 [0..22] [1049..42]
gi|88180750, gi|... - gi|88180750|gb|EAQ88218.1| hypothetical protein CHGG_04837 [Chaetomium globosum CBS 148.51], gi|1161...
987.0 [0..10] [1049..3]
gi|83765331 - gi|83765331|dbj|BAE55474.1| unnamed protein product [Aspergillus oryzae]
gi|169766010 - gi|169766010|ref|XP_001817476.1| hypothetical protein [Aspergillus oryzae RIB40]
983.0 [0..20] [1049..8]
gi|115399962, gi... - gi|115399962|ref|XP_001215570.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
972.0 [0..16] [1049..24]
gi|70986961, gi|... - gi|70986961|ref|XP_748966.1| nonsense-mediated mRNA decay factor (Upf2) [Aspergillus fumigatus Af293...
944.0 [0..9] [1049..2]
gi|114629521 - gi|114629521|ref|XP_507656.2| PREDICTED: UPF2 regulator of nonsense transcripts homolog [Pan troglod...
937.0 [0..3] [1047..290]
gi|109506162 - gi|109506162|ref|XP_001071022.1| PREDICTED: similar to UPF2 regulator of nonsense transcripts homolo...
919.0 [0..3] [1047..113]

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Predicted Domain #1
Region A:
Residues: [1-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSREEQIKKL NQYLDNRELA FRAKDGDKNI FHTESQLDSS LKKNTAFMKR CKSSLTSENY  60
   61 DSFIKEIKTL SLKKFIPEIT AAIVEGMMKC KATKDILSSV KIVWALNLRF STAFTGPMLA 120
  121 NLYCALYPNP GYSLCHESYF ELKQNENEVS EKDRSSHLLK VRPLLRFLIE FWLNGVVGTP 180
  181 EDFVSYLPST DSNDKKFRKP WFEEQNLKKP LVVLLFNDLM DTRFGFLLLP VLTSLVRTFS 240
  241 CELFTTEDFE DKETLELVNR LNPVVWRTYL RKSLNSYVDK LEVYCQKRKS LFEELNKQYQ 300
  301 EQSIIRADPN NEKFQRLANF SKSIESEFSS YASLSEVLNR KASEDLLELN FMEKASSGTN 360
  361 SVFNASGERS ESANVETAQV WDDREQYFFY EVFPNFNEGS IAEMKSSIYE SSQEGIRSSS 420
  421 ENNKKEDDLK 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.18
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.34835981020148 bayes_pls_golite062009
protein binding 0.591747388847465 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [431-643]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSTGDLNTTQ VSSRVDNFLL KLPSMVSLEL TNEMALEFYD LNTKASRNRL IKALCTIPRT  60
   61 SSFLVPYYVR LARILSQLSS EFSTSLVDHA RHSFKRMIHR KAKHEYDTRL LIVRYISELT 120
  121 KFQLMPFHMV FECYKLCINE FTPFDLEVLA LLLESCGRFL LRYPETKLQM QSFLEAIQKK 180
  181 KLASALASQD QLVLENALHF VNPPKRGIIV SKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.09691
Match: 1hu3A
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.11573661150436 bayes_pls_golite062009
binding 1.83406697369076 bayes_pls_golite062009
protein binding 1.04044934052933 bayes_pls_golite062009
nucleic acid binding 0.967597910409065 bayes_pls_golite062009
mRNA binding 0.73831124805124 bayes_pls_golite062009
hydrolase activity 0.0579816100130538 bayes_pls_golite062009
transcription regulator activity 0.022274123463527 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [644-882]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSLKEEFLYD LIQIRLKDDN VFPTLLLLRK FDWKDDYQIL YNTIMEVWNI KYNSLNALAR  60
   61 LLSALYKFHP EFCIHVIDDT LESLFSAVNN SDHVEKQKRL AQARFISELC VIHMLDVRAI 120
  121 TNFLFHLLPL EKFESFLTMK ASTLTNINND MFRLRLIVVV LQTCGPSIIR SKTKKTMLTY 180
  181 LLAYQCYFLI QPEMPLDMLY EFEDVIGYVR PSMKVYMHYE EARNALTERL QAISDDWEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.522879
Match: 1uw4B
Description: The structural basis of the interaction between nonsense mediated decay factors UPF2 and UPF3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.11573661150436 bayes_pls_golite062009
binding 1.83406697369076 bayes_pls_golite062009
protein binding 1.04044934052933 bayes_pls_golite062009
nucleic acid binding 0.967597910409065 bayes_pls_golite062009
mRNA binding 0.73831124805124 bayes_pls_golite062009
hydrolase activity 0.0579816100130538 bayes_pls_golite062009
transcription regulator activity 0.022274123463527 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [883-1049]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDTRPVFQGA NDGDISSNEE SVYLPEDISD ESETDEESSG LEESDLLDSE DEDIDNEMQL  60
   61 SRELDEEFER LTNESLLTRM HEKNPGFDVP LPLRASSLGS PYVTRNEESA SESSHVMFTL 120
  121 LTKRGNKQRS QYLEIPSHSS LVRSTKNQQT EEIMERKRVK EMVLNFE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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