YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|58372449, gi\|...
Organism:	Plasmodium falciparum
Length:	590 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|58372449, gi|....

Description	E-value	Query Range	Subject Range
gi\|58372441, gi\|... - gi\|58372447\|gb\|AAW71467.1\| plasmepsin 5 [Plasmodium falciparum], gi\|58372441\|gb\|AAW71464.1\| plasmeps...	338.0	[0..1]	[590..1]
APA1_ARATH - Aspartic proteinase A1 OS=Arabidopsis thaliana GN=APA1 PE=1 SV=1	319.0	[0..4]	[516..1]
gi\|21616051 - gi\|21616051\|emb\|CAC86003.1\| aspartic proteinase [Theobroma cacao]	314.0	[0..12]	[516..12]
gi\|20800441, gi\|... - gi\|33339734\|gb\|AAQ14346.1\| aspartic proteinase [Vigna unguiculata], gi\|20800441\|gb\|AAB03843.2\| aspar...	312.0	[0..1]	[516..1]
gi\|1326165, gi\|7... - pir\|\|T07915 probable aspartic proteinase (EC 3.4.23.-) 1 - rape, gi\|1326165\|gb\|AAB03108.1\| aspartic ...	306.0	[0..9]	[516..9]
gi\|125553350 - gi\|125553350\|gb\|EAY99059.1\| hypothetical protein OsI_21016 [Oryza sativa Indica Group] ASPR1_ORYSA - Aspartic proteinase oryzasin-1 precursor (EC 3.4.23.-) - Oryza sativa (Rice) ASPR1_ORYSJ - Aspartic proteinase oryzasin-1 OS=Oryza sativa subsp. japonica GN=Os05g0567100 PE=2 SV=2	304.0	[0..24]	[516..22]
gi\|46488439, gi\|... - gi\|46488455\|gb\|AAS99549.1\| aspartic protease PM5 [Plasmodium vivax], gi\|46488449\|gb\|AAS99546.1\| aspa...	304.0	[0..90]	[585..52]

Back

Predicted Domain #1

Region A:
Residues: [1-527]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNYFLRKEN FFILFCFVFV SIFFVSNVTI IKCNNVENKI DNVGKKIENV GKKIGDMENK  60
   61 NDNVENKNDN VGNKNDNVKN ASSDLYKYKL YGDIDEYAYY FLDIDIGKPS QRISLILDTG 120
  121 SSSLSFPCNG CKDCGIHMEK PYNLNYSKTS SILYCNKSNC PYGLKCVGNK CEYLQSYCEG 180
  181 SQIYGFYFSD IVTLPSYNNK NKISFEKLMG CHMHEESLFL HQQATGVLGF SLTKPNGVPT 240
  241 FVDLLFKHTP SLKPIYSICV SEHGGELIIG GYEPDYFLSN QKEKQKMDKS DNNSSNKGNV 300
  301 SIKLKNNDKN DDEENNSKDV IVSNNVEDIV WQAITRKYYY YIKIYGLDLY GTNIMDKKEL 360
  361 DMLVDSGSTF THIPENIYNQ INYYLDILCI HDMTNIYEIN KRLKLTNESL NKPLVYFEDF 420
  421 KTALKNIIQN ENLCIKIVDG VQCWKSLENL PNLYITLSNN YKMIWKPSSY LYKKESFWCK 480
  481 GLEKQVNNKP ILGLTFFKNK QVIFDLQQNQ IAFIESKCPS NLTSSRP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.221849
Match:	1qdmA
Description:	(Pro)phytepsin; Plant acid proteinase, phytepsin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.01508543827677	bayes_pls_golite062009
hydrolase activity	0.77554493777157	bayes_pls_golite062009
peptidase activity	0.68518523369811	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.43925265235199	bayes_pls_golite062009
endopeptidase activity	0.43264884039584	bayes_pls_golite062009
aspartic-type endopeptidase activity	0.30585066730542	bayes_pls_golite062009
aspartic-type peptidase activity	0.30585066730542	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [528-590]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTFNEYREKE NIFLKVSYIN LYCLWLLLAL TILLSLILYV RKMFYMDYFP LSDQNKSPIQ  60
   61 EST

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.1
Match:	1eysH
Description:	Photosynthetic reaction centre; Photosystem II reaction centre subunit H, transmembrane region
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: