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View Structure Prediction Details

Protein: ARP5_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 721 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARP5_SCHPO.

Description E-value Query
Range
Subject
Range
gi|109489498 - gi|109489498|ref|XP_001076100.1| PREDICTED: similar to Actin, cytoplasmic 2 (Gamma-actin) [Rattus no...
418.0 [0..7] [362..297]
gi|45269029 - gi|45269029|gb|AAS55927.1| cytoskeletal beta actin [Sus scrofa]
412.0 [0..18] [362..28]
gi|94392330 - gi|94392330|ref|XP_999478.1| PREDICTED: similar to Actin, cytoplasmic 2 (Gamma-actin) [Mus musculus]
411.0 [0..22] [362..212]
gi|223855 - gi|223855|prf||1002250A actin
410.0 [0..21] [362..1]
ACT1_DICDI - (P02577) Actin
409.0 [0..20] [362..1]
gi|29293659 - gi|29293659|gb|AAO67718.1| beta actin [Engystomops pustulosus]
408.0 [0..22] [362..5]
ACTB_XENBO - Actin, cytoplasmic 1 OS=Xenopus borealis GN=actb PE=3 SV=1
408.0 [0..22] [362..4]

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Predicted Domain #1
Region A:
Residues: [1-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIYAVREPV FSGPTPSFQN VSNDIPLVID NGSWQLRAGW GGEKDPKLVF DNLVSRYRDR  60
   61 KLSRTSTLVG NDTLIEVGSR SIARSPFERN VISNWDLMEQ VLDYTFLKLG IDRMEHPICM 120
  121 TEPLANPTYV RSTMTELLFE LYNAPSVAYG IDGLFSFYHN TKPSSSGIVL NLGNAASHVI 180
  181 PVLNGER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 1nlvA
Description: Actin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.49917339467744 bayes_pls_golite062009
structural constituent of cytoskeleton 3.14961582364442 bayes_pls_golite062009
cytoskeletal protein binding 3.11425505645918 bayes_pls_golite062009
DNA helicase activity 2.92189100911743 bayes_pls_golite062009
myosin binding 2.53108346927043 bayes_pls_golite062009
actin filament binding 2.01821925799878 bayes_pls_golite062009
binding 1.97067859459221 bayes_pls_golite062009
histone acetyltransferase activity 1.59975673209166 bayes_pls_golite062009
lysine N-acetyltransferase activity 1.59975673209166 bayes_pls_golite062009
protein binding 0.979596124775086 bayes_pls_golite062009
DNA-dependent ATPase activity 0.726191454623287 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.654083598964358 bayes_pls_golite062009
structural molecule activity 0.592226835455977 bayes_pls_golite062009
nucleosome binding 0.329990231856661 bayes_pls_golite062009
transcription coactivator activity 0.181830769846903 bayes_pls_golite062009
kinase activity 0.123127976437259 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0670632180760572 bayes_pls_golite062009
N-acetyltransferase activity 0.0571907728331915 bayes_pls_golite062009
chromatin binding 0.0424425838189793 bayes_pls_golite062009
5'-3' DNA helicase activity 0.0183211661451317 bayes_pls_golite062009
ATP-dependent 5'-3' DNA helicase activity 0.0183211661451317 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [188-582]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILSEAKRISW GGSQSSSYLL KLFQIKYPSF PIKMLPSQAE LLMHDHCHVS SDYTHDIAHA  60
   61 LDRDILERDE IVLQFPYTEA AAQEKSQEEL ELIAERKRES GRRLQAQAAI KRKEKAAERD 120
  121 RELATLTELQ QQSLVLSRRA FQRALEEAGF EDESQLNAQV KNVQAKIRRA QRDQQRQEES 180
  181 EGSLDVTEID VEQAFPLLNV PDAELDEAGL RQKRHQRLMK ANYDARVRAK AEKAIEEAAE 240
  241 AERAEADERL RLENFSTWVN EKRETHKILL EKISKNKRLK FELNDRKSHA SQMRMKSLAT 300
  301 LASEQPIQKR KRKDQSEDNF GARDEDWKVY HDVLTAEQLE EERKKLLDQI YSLEKQLLEY 360
  361 DSQFTQANTY DTLNDPRATL LYAFTRGVSD FDVND

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [583-721]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAQAFQLHLN VEQIRVPEVI FSPSIVGIDQ AGILEIMRSI LQRHSLEEQQ KLVSNVLITG  60
   61 GLGSLPGMET RIKRELTSIM PVGSSINVFR ASNPLLDAWK GASEWSVTEK FKAAKVTREE 120
  121 YLEKGPEYIK EHSLGNINS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.81
Match: 1eqyA
Description: Actin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle