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View Structure Prediction Details

Protein: SIP5_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 554 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIP5_SCHPO.

Description E-value Query
Range
Subject
Range
SIP5_ASHGO - Protein SIP5 OS=Ashbya gossypii GN=SIP5 PE=3 SV=1
SIP5_ASHGO - Protein SIP5 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=SIP5 P...
449.0 [0..9] [376..87]
SIP5_CANAL - Protein SIP5 OS=Candida albicans GN=SIP5 PE=3 SV=1
SIP5_CANAL - Protein SIP5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SIP5 PE=3 SV=1
437.0 [0..7] [372..72]
SIP5_NEUCR - Protein sip-5 OS=Neurospora crassa GN=sip-5 PE=3 SV=1
SIP5_NEUCR - Protein sip-5 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 98...
411.0 [0..7] [365..90]
SIP5 - Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase
SIP5_YEAST - Protein SIP5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIP5 PE=1 SV=1
406.0 [0..9] [381..85]
gi|46127501, gi|... - gi|46127501|ref|XP_388304.1| hypothetical protein FG08128.1 [Gibberella zeae PH-1], gi|42549084|gb|E...
405.0 [0..6] [369..90]
SIP5_ASPFU - Protein sip5 OS=Aspergillus fumigatus GN=sip5 PE=3 SV=1
SIP5_ASPFU - Protein sip5 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=sip...
374.0 [0..7] [369..92]
SIP5_ASPOR - Protein sip5 OS=Aspergillus oryzae GN=sip5 PE=3 SV=1
SIP5_ASPOR - Protein sip5 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) GN=sip5 PE=3 SV=1
362.0 [0..7] [367..88]
SIP5_EMENI - Protein sip5 OS=Emericella nidulans GN=sip5 PE=3 SV=1
SIP5_EMENI - Protein sip5 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=...
359.0 [0..7] [367..94]
SIP5_CANGA - Protein SIP5 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=...
SIP5_CANGA - Protein SIP5 OS=Candida glabrata GN=SIP5 PE=3 SV=1
352.0 [0..9] [372..92]
gi|114196975, gi... - gi|115490975|ref|XP_001210115.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
347.0 [0..7] [367..86]

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Predicted Domain #1
Region A:
Residues: [1-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNTIGKERQ ENDEELIQHL VQLVDGGFLD PQGVYSSAPA YKTNIVRKLM LERRLMPFYK  60
   61 GLDSYSKDWP ADKVVEVVEK ALGPHKSALL HCAIRQSRSL SVGNTRSLKR DSRGSSDHLL 120
  121 TRNRSNSTPG SISADYRTTA ITTIYANAME CPICFLYYPS NFNYTRCCAQ PICSECFVEI 180
  181 RRAEPHLPTV HANEPTPNEF DLISEPAKCP YCMTERFGVI YKPNPKLTPF SFNNNPDTLP 240
  241 SNIAPMGTLS KSSLPLHHIP WPPNQHIKFA HDDKNVVST

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.991
Match: 1dvpA
Description: Hrs
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.18807294523099 bayes_pls_golite062009
protein binding 1.3899161465056 bayes_pls_golite062009
hydrolase activity 0.612485742121248 bayes_pls_golite062009
clathrin binding 0.536431227881258 bayes_pls_golite062009
DNA binding 0.323179972743082 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [280-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFIHPDWQYK LERARRRALR RAANATLLNS HLLETGPANA NANHNTDLSH DPTSHGGPRR  60
   61 TLSSRRQHYL ANVEQLMLAE AIRQSLLDAQ SNDSTNS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.322 0.913 vacuolar membrane a.47.2 t-snare proteins
View Download 0.513 0.029 vacuolar membrane a.133.1 Phospholipase A2, PLA2
View Download 0.314 0.001 vacuolar membrane a.24.11 Bacterial GAP domain
View Download 0.266 0.001 vacuolar membrane a.130.1 Chorismate mutase II
View Download 0.412 0.001 vacuolar membrane a.46.1 Methionine synthase domain

Predicted Domain #3
Region A:
Residues: [377-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSTEVSQPD STNISNEQEI VQPQPTHTTN VALVEEINRP DSVESAITAS SSIDTGNENE  60
   61 TQEVNSDSLP QFVHQTMTQT NFQESSPSVA ADETRVHNVD EYIEQQDLDE LIHSPIASTN 120
  121 PFLADQFARS ETVDLNAHIC SPALSVSDDG VTATNKTQSS FPSVYEHQLK SNELERGH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle