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View Structure Prediction Details

Protein: GHT8_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 547 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GHT8_SCHPO.

Description E-value Query
Range
Subject
Range
ght5 - hexose transporter Ght5
GHT5_SCHPO - High-affinity glucose transporter ght5 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ght...
288.0 [0..1] [547..1]
orf19.2020, orf1... - HGT6 CGDID:CAL0004351 Assembly 19, Contig19-10139 (66413, 64761) CDS, reverse complemented, translat...
gi|68472555, gi|... - gi|68472808|ref|XP_719469.1| potential hexose transporter [Candida albicans SC5314], gi|68472555|ref...
264.0 [0..8] [507..52]
gi|115402325, gi... - gi|115402325|ref|XP_001217239.1| hypothetical protein ATEG_08653 [Aspergillus terreus NIH2624], gi|1...
264.0 [0..5] [483..48]
SNF3 - Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmemb...
SNF3_YEAST - High-affinity glucose transporter SNF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=S...
262.0 [0..11] [536..102]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
261.0 [0..8] [499..64]
gi|49527412 - gi|49527412|emb|CAG61052.1| unnamed protein product [Candida glabrata]
gi|50291337, gi|... - gi|50291337|ref|XP_448101.1| unnamed protein product [Candida glabrata], gi|49527412|emb|CAG61052.1|...
260.0 [0..7] [534..120]

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Predicted Domain #1
Region A:
Residues: [1-458]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKTLTIVML VFVSMAGWMF GADTGSIGGI TNMRDFQSRF ADRYNPVTDT YSYSSARQGL  60
   61 ITGMVNVGSM TGCILSSPLM DRIGKRVSIM FWTIVYLIGI ILQVTAVPSW VQIMVAKIWT 120
  121 GLAIGALSVL APGFQSEVAP ATLRGTIVTT YQLAVTGGIF IAACINMGTH KLHKTAQWRV 180
  181 SMGINLLWGI IMFIGISFLP ESPRYLIAIG KDEEALDIMC KNNVLPREHE IIQTEYHVIK 240
  241 TDCEAEMAGG PATWGDILGA DIRYRTFLGL GVMSLQQLTG DNYYFYYGFE VFEGTGMNSP 300
  301 YLSALILDAV NFGCTFGGLF VLEFFGRRMP LIIGGVWQSI TFFIYAAVGN RALTRKNGTS 360
  361 NHRAGAVMIV FSCLFIFSFA QTWGPAAYVI VGESYPIRYR SKCAAVATTG NWLWGFLITF 420
  421 FTPFISDSIG FKYGYIFAAC NLCAACIIFL FAHETKGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.221849
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycerol transmembrane transporter activity 7.11654923455995 bayes_pls_golite062009
alcohol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
polyol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity 5.74077413704789 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 2.63293544825311 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.46605775041083 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [459-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLEEINELYL SGAKPWMPRP ENLGQAAKQQ QEVLEKSRGV QGESAAHLEN VDNEGMEDTS  60
   61 SNDITSSTSS SEGRAKPESN YVDEQDRYA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle