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View Structure Prediction Details

Protein: UCRI_MOUSE
Organism: Mus musculus
Length: 274 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UCRI_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109099172, gi... - gi|109099174|ref|XP_001101289.1| PREDICTED: ubiquinol-cytochrome c reductase, Rieske iron-sulfur pol...
264.0 [0..1] [274..1]
UCRI_CHLAE - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Chlorocebus aethiops GN=UQCRFS1 PE=3 SV=1
263.0 [0..1] [274..1]
UCRI_THEGE - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Theropithecus gelada GN=UQCRFS1 PE=3 SV=1
263.0 [0..1] [274..1]
UQCRFS1 - ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
gi|39939354 - gi|39939354|gb|AAR32728.1| ubiquinol-cytochrome c oxidoreductase subunit 9 and Rieske iron sulfur pr...
gi|123981876 - gi|123981876|gb|ABM82767.1| ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [synt...
UCRI_GORGO - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Gorilla gorilla gorilla GN=UQCRFS1 PE=3 SV=...
262.0 [0..1] [274..1]
UCRI_PANPA - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Pan paniscus GN=UQCRFS1 PE=3 SV=1
UCRI_PANTR - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Pan troglodytes GN=UQCRFS1 PE=3 SV=1
261.0 [0..1] [274..1]
UCRI_RAT - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Rattus norvegicus GN=Uqcrfs1 PE=1 SV=2
261.0 [0..1] [274..1]
UCRI_SYMSY - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Symphalangus syndactylus GN=UQCRFS1 PE=3 SV...
259.0 [0..1] [274..1]
UCRI_PONPY - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Pongo pygmaeus GN=UQCRFS1 PE=3 SV=1
259.0 [0..1] [274..1]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSVAARSGP FAPVLSATSR GVAGALRPLL QGAVPAASEP PVLDVKRPFL CRESLSGQAA  60
   61 ARPLVATVGL NVPASVRFSH TDVKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1be3I
Description: CYTOCHROME BC1 COMPLEX FROM BOVINE
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [86-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDFSDYRRAE VLDSTKSSKE SSEARKGFSY LVTATTTVGV AYAAKNVVSQ FVSSMSASAD  60
   61 VLAMSKIEIK LSDIPEGKNM AFKWRGKPLF VRHRTKKEID QEAAVEVSQL RDPQHDLDRV 120
  121 KKPEWVILIG VCTHLGCVPI ANAGDFGGYY CPCHGSHYDA SGRIRKGPAP LNLEVPAYEF 180
  181 TSDDVVVVG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.0
Match: 1bccE
Description: ISP subunit of the mitochondrial cytochrome bc1-complex, watersoluble domain; Iron-sulfur subunit (ISP) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane region
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquinol-cytochrome-c reductase activity 12.5243667017255 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 12.5243667017255 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 9.125468664417 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 6.56410033542443 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 6.40889163290296 bayes_pls_golite062009
oxidoreductase activity 6.05060612159037 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 5.79350583896014 bayes_pls_golite062009
cation transmembrane transporter activity 5.52425708699797 bayes_pls_golite062009
ion transmembrane transporter activity 5.31511996363681 bayes_pls_golite062009
electron carrier activity 5.20213585732279 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.88364619884033 bayes_pls_golite062009
substrate-specific transporter activity 4.66567624087954 bayes_pls_golite062009
catalytic activity 0.746741393172769 bayes_pls_golite062009
binding 0.742487129233448 bayes_pls_golite062009
iron-sulfur cluster binding 0.71220774812099 bayes_pls_golite062009
metal cluster binding 0.71220774812099 bayes_pls_golite062009
protein binding 0.125309487167241 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle